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View Structure Prediction Details

Protein: twk-23
Organism: Caenorhabditis elegans
Length: 452 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for twk-23.

Description E-value Query
Range
Subject
Range
gi|47077078 - gi|47077078|dbj|BAD18468.1| unnamed protein product [Homo sapiens]
204.0 [0..72] [450..167]

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Predicted Domain #1
Region A:
Residues: [1-59]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTMCLRSTR NIFYPYFSPI VANKQKLKCN SKCAWMKFRN VLRIALGHLA LYCFVVCYV

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [60-324]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FAGAWVFHQL EGENETELHD KQREYAMNLK KDVIAKLATT ENVAEINEHL RMFLRNISNL  60
   61 HISLDNYLIF NEPTQIVPKR WTFPSSVLFS FTILTTIGYG NVTPHTQQCK VFLMIYGAFG 120
  121 IPLFLITIAD LGRFSKTAIM ALVQKVSKRE LKKQSDEHLL REIAEVSPYL DVLLVAGLFV 180
  181 VFIAIGSAVI PLWENQLTYF DSVYFSYMSL TTIGLGDIVP RRMDFLLPTL IYITIGLWLT 240
  241 TALVEQLADV FRLVHYAGRQ VTNVK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 21.69897
Match: 2a79B
Description: Mammalian Shaker Kv1.2 potassium channel- beta subunit complex
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [325-452]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GITVWLGGRR LSMGGLISTV CRRVGMSDNL INQINWDRTV IDALDGKMPP TLPIFPWHFT  60
   61 DFLEHDPPLI DLSIDLDQMD GSFYCSKPLS AKKQRRASQM SAPAISWMRP QEEARILDAD 120
  121 GTFPNIDA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.30103
Match: 2q0aA
Description: No description for 2q0aA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle