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View Structure Prediction Details

Protein: cdc-25.2
Organism: Caenorhabditis elegans
Length: 480 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for cdc-25.2.

Description E-value Query
Range
Subject
Range
gi|190691881, gi... - gi|190691881|gb|ACE87715.1| cell division cycle 25 homolog C (S. pombe) protein [synthetic construct...
CDC25C - cell division cycle 25 homolog C (S. pombe)
285.0 [0..1] [389..60]

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Predicted Domain #1
Region A:
Residues: [1-131]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNRPSQISQD VAQPLSNQHE TAMMSSDEDS MSRDSGICEL MDENTPVCFS SMSTESTTVQ  60
   61 VEECMEIDED ENLQPGPVSR RQKKVTFRRE KSSCQVRLFD ESPTSHKMFM RPQAPLSVRS 120
  121 ENQQLLQQRK R

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [132-390]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KFEKSEQSSD HFHLEPMSVE AMDDDEIVMM DQNTTKWEPG FRAPNHKKGR LTRSATAFPS  60
   61 LETFEEEEHE EQHHLNVKYH LKTVAKESSK GFRRITAETL RDIFFRLSEK EFDDKYILID 120
  121 CRYPYEYNRG HIKNAINHFD RVTVSKIFYD ENGRKRCNKI PIFYCEFSQA RGPKMAYALR 180
  181 QVDRELNVNH YPKCDYEEMY VLDLGYRNFF FAANEANITN LCQPHAYCEM HDKEHTMELK 240
  241 KYNFHNKGQS VLRTVSMSR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 47.0
Match: 1cwrA
Description: CDC25b
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.19146849441852 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [391-480]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SFKSLPTGSA FNFVASSASF TSAPSTSTEN IDTNDDCQKS RTPAVPRIAS RRNLFSDPSH  60
   61 SPTNFAQFPL TCSRETPSPH KHPLTCPRFS 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle