YRC Public Data Repository - Protein Structure Prediction

Protein:	frh-1
Organism:	Caenorhabditis elegans
Length:	136 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for frh-1.

Description	E-value	Query Range	Subject Range
gi\|187037329, gi... - gi\|39596993\|emb\|CAE59220.1\| Hypothetical protein CBG02538 [Caenorhabditis briggsae], gi\|187037329\|em... gi\|157751916 - gi\|157751916\|ref\|XP_001679670.1\| Hypothetical protein CBG02538 [Caenorhabditis briggsae AF16]	176.0	[0..1]	[136..1]
FXN - frataxin	167.0	[0..6]	[133..78]
gi\|109463707 - gi\|109463707\|ref\|XP_001078791.1\| PREDICTED: similar to Frataxin, mitochondrial precursor (Fxn) [Ratt...	167.0	[0..6]	[133..76]
FRDA_MOUSE - Frataxin, mitochondrial OS=Mus musculus GN=Fxn PE=1 SV=1	166.0	[0..6]	[133..75]
gi\|109111727 - gi\|109111727\|ref\|XP_001093449.1\| PREDICTED: similar to frataxin isoform 1 preproprotein [Macaca mula...	164.0	[0..6]	[133..78]
fh-PA - The gene frataxin homolog is referred to in FlyBase by the symbol Dmel\fh (CG8971, FBgn0030092). It ... gi\|220949572 - gi\|220949572\|gb\|ACL87329.1\| fh-PA [synthetic construct]	164.0	[0..10]	[134..53]
FRDA_MACFA - Frataxin, mitochondrial OS=Macaca fascicularis GN=FXN PE=2 SV=1	161.0	[0..6]	[133..78]

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Predicted Domain #1

Region A:
Residues: [1-136]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSTILRNNF VRRSFSSRIF SQNEYETAAD STLERLSDYF DQIADSFPVS EQFDVSHAMG  60
   61 VLTVNVSKSV GTYVINKQSP NKQIWLSSPM SGPKRYDLEE EGKWTYAHDG EQLDSLLNRE 120
  121 FRKILADDRI DFSRHV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	37.045757
Match:	1ekgA
Description:	C-terminal domain of frataxin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	0.643026615473467	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: