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View Structure Prediction Details

Protein: hmit-1.1
Organism: Caenorhabditis elegans
Length: 606 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for hmit-1.1.

Description E-value Query
Range
Subject
Range
gi|49527412 - gi|49527412|emb|CAG61052.1| unnamed protein product [Candida glabrata]
gi|50291337, gi|... - gi|50291337|ref|XP_448101.1| unnamed protein product [Candida glabrata], gi|49527412|emb|CAG61052.1|...
289.0 [0..2] [438..97]

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Predicted Domain #1
Region A:
Residues: [1-457]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVAVAAFSSS GQDKPAHTPK LGLFVYILAA ASVIGGFLFG YDTSVVSAAM LYMPDAPGLK  60
   61 PMDTVWQEVL VSISPGMAAV GSLMSGTSSD YIGRRKVILG ASAIFTIGAL VCAASVNKIM 120
  121 LLVGRVLLGI AIGFASMIVP VYLGETAPTH VRGMLVAAFA LMISFGQVVA NITGGAFSYI 180
  181 DPYNVGWRLM FAFAAVPSII QFVCFMFLPE TPRWLYENGF ETETREVLEK VYNGDKEWVE 240
  241 YEMAEIIAFN EDQAKENEKA HASGPVIWRI LKTPHVLKAC FIGSMLQAFQ QLAGINTILY 300
  301 YTADIIRSSG ISNNHTTIWI SVLLSLCNFI GPFVPMSLIE KVGRRIIFLF SCGLVVLSLV 360
  361 FIGVAFLLVN HDSAATLPAN QYGSNFNSSY PDAKGCMAYS NCDYCVTTDA CGFCHDANTK 420
  421 QGYCLPAGFD NPEVYSSTGS CTNSNGSIAN NFKWEKY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 22.69897
Match: 1pw4A
Description: Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transporter activity 4.09176719149278 bayes_pls_golite062009
substrate-specific transporter activity 3.59744164024479 bayes_pls_golite062009
transmembrane transporter activity 3.5865018981083 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 3.54194478414824 bayes_pls_golite062009
hexose phosphate transmembrane transporter activity 3.29248638217469 bayes_pls_golite062009
glucose-6-phosphate transmembrane transporter activity 3.29248638217469 bayes_pls_golite062009
sugar:hydrogen symporter activity 2.99050613058546 bayes_pls_golite062009
cation:sugar symporter activity 2.99050613058546 bayes_pls_golite062009
carbohydrate transmembrane transporter activity 2.62141276633776 bayes_pls_golite062009
sugar transmembrane transporter activity 2.47557586092261 bayes_pls_golite062009
ion transmembrane transporter activity 2.21266150105753 bayes_pls_golite062009
solute:hydrogen symporter activity 2.10485633822652 bayes_pls_golite062009
cation transmembrane transporter activity 1.79369588808394 bayes_pls_golite062009
monosaccharide transmembrane transporter activity 1.6904339767429 bayes_pls_golite062009
active transmembrane transporter activity 1.59419818573076 bayes_pls_golite062009
binding 1.46605775041083 bayes_pls_golite062009
secondary active transmembrane transporter activity 1.22264637452409 bayes_pls_golite062009
polyol transmembrane transporter activity 0.924836669821548 bayes_pls_golite062009
alcohol transmembrane transporter activity 0.924836669821548 bayes_pls_golite062009
glycerol transmembrane transporter activity 0.812001619402678 bayes_pls_golite062009
symporter activity 0.74591237387473 bayes_pls_golite062009
solute:cation symporter activity 0.74591237387473 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [458-606]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YCDTKYTLLP IIACGVYLLT FSSGFTSLPW VLNSEFYPMW ARSTCVAIST TSNWVFNLII  60
   61 ALTYLSLTQV IGKYGAFWLY AGLTVIAFIF ILFLVPETKG YSIEEVEMLF MNKKQRREAE 120
  121 SRRRETVTEV RSRMNSTVSF GQHNEVHKY

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.18
Match: 1pw4A
Description: Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle