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View Structure Prediction Details

Protein: cyk-4
Organism: Caenorhabditis elegans
Length: 681 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for cyk-4.

Description E-value Query
Range
Subject
Range
gi|109124072 - gi|109124072|ref|XP_001115784.1| PREDICTED: GEM interacting protein [Macaca mulatta]
257.0 [0..12] [677..1774]

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Predicted Domain #1
Region A:
Residues: [1-299]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKSSTSKEKV CGENSRHIFN MILNSQRPQF DIKDIGMFHL IDEIERLRKL WKDSEESKKR  60
   61 LNADMREAEE ALAKARKKLA MFDIDVKDTQ KHLRALMEEN KALKLDLNVY ETREKQLKDA 120
  121 MKNGIFNSLT KEDRDQFKFL HEPLVRTYSK RVQQRHPHLM EDTQDDEDDS EVDYDETGDS 180
  181 FEEVIHLRNG REVRRSSAAG NAVGGKRRSA SAHAITAAAN SKRSRSRVMT ATIDEEPNEG 240
  241 GTPPKRCRDD GSTPHQEMTT TTTTTTTTTI HNSRAQNQDP PRVSLHRQLT RRSLSCGSI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 11.522879
Match: 2i1jA
Description: No description for 2i1jA was found.

Predicted Domain #2
Region A:
Residues: [300-681]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSCDQTPGQT TNNIGLGMSS AILTKSTLDI RTLKRGTPAW TNGTTRDIAM RPHTFIEAGI  60
   61 KAMRKCDKCA TALKLATSMK CRDCHQVVHR SCCNKLHLPC IPRPKTMMTP KSALRGAKPG 120
  121 AGEFRLQDFC TSAKPMIPAA VIHCVVALEA RGLTQEGIYR VPGQVRTVNV LLDELRSKTV 180
  181 PNVGLHDVEV ITDTLKRFLR DLKDPLIPRT SRQELIVAAN LYSTDPDNGR LALNRVICEL 240
  241 PQANRDTLAY LFIHWRKVIA QSSRNKMNCE AMARMVAPAV MGHPVKQSQS QAIAGRDATD 300
  301 CHRAMTALFE FDDVYWQRFL GTSAVSMASN QIETARHQDN FALCDRSILG PVTTSPATPL 360
  361 LARSANATRA RGAHLLGSMF HD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 49.09691
Match: 1xa6A
Description: Crystal Structure of the Human Beta2-Chimaerin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.01489434558857 bayes_pls_golite062009
GTPase activator activity 0.887637072280891 bayes_pls_golite062009
Rho GTPase activator activity 0.8316603048119 bayes_pls_golite062009
protein binding 0.595458677481796 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle