YRC Public Data Repository - Protein Structure Prediction

Protein:	CE18659
Organism:	Caenorhabditis elegans
Length:	242 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE18659.

Description	E-value	Query Range	Subject Range
gi\|73963080 - gi\|73963080\|ref\|XP_852144.1\| PREDICTED: similar to protein phosphatase 1A isoform 1 isoform 3 [Canis...	194.0	[0..16]	[241..6]
PPM1A_RABIT - Protein phosphatase 1A OS=Oryctolagus cuniculus GN=PPM1A PE=2 SV=1	194.0	[0..16]	[241..6]
PPM1A_RAT - Protein phosphatase 1A OS=Rattus norvegicus GN=Ppm1a PE=1 SV=1	193.0	[0..16]	[241..6]
gi\|50748830 - gi\|50748830\|ref\|XP_421422.1\| PREDICTED: similar to protein phosphatase 2C alpha; PP2Calpha [Gallus g...	193.0	[0..16]	[241..6]
CCDS9744.1_1 - null PPM1A - protein phosphatase, Mg2+/Mn2+ dependent, 1A gi\|114653343, gi... - gi\|114653347\|ref\|XP_509986.2\| PREDICTED: hypothetical protein LOC452950 isoform 9 [Pan troglodytes],... gi\|109083826, gi... - gi\|109083828\|ref\|XP_001096358.1\| PREDICTED: similar to protein phosphatase 1A isoform 1 isoform 5 [M... gi\|123996549, gi... - gi\|168279063\|dbj\|BAG11411.1\| protein phosphatase 1A [synthetic construct], gi\|123996549\|gb\|ABM85876....	193.0	[0..16]	[241..6]
PPM1A_MOUSE - Protein phosphatase 1A OS=Mus musculus GN=Ppm1a PE=1 SV=1	193.0	[0..16]	[241..6]
gi\|114584139 - gi\|114584139\|ref\|XP_001152781.1\| PREDICTED: integrin-linked kinase-associated protein phosphatase 2C...	193.0	[0..6]	[241..242]
PPM1A_BOVIN - Protein phosphatase 1A OS=Bos taurus GN=PPM1A PE=2 SV=1	193.0	[0..16]	[241..6]
gi\|109083832 - gi\|109083832\|ref\|XP_001095896.1\| PREDICTED: similar to protein phosphatase 1A isoform 1 isoform 1 [M...	192.0	[0..16]	[241..6]

Back

Predicted Domain #1

Region A:
Residues: [1-242]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYSDSRKRSS DDLIDNSDES KKPKESRNLY CTLAAYGCRK GERADMQDTH IMLPKFDLGT  60
   61 EKSFLSRASF FAIFDGHAGP RAAEHCQSQM GKTVKEKLAK FSDFPTLTKS LKQTFTESYK 120
  121 AVDDGFLAIA KQNKPIWKDG TTATTMIILN NVIYVANIGD SRAVVARKKE DGSFAPVCLT 180
  181 VDHDPMSHDE RMRIQKAGAV VKDGRINGVI EVSRSIGDLP FKSLGIISTP DLKKLTLTKN 240
  241 DL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	49.522879
Match:	1a6qA
Description:	CRYSTAL STRUCTURE OF THE PROTEIN SERINE/THREONINE PHOSPHATASE 2C AT 2 A RESOLUTION
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.00395346056763	bayes_pls_golite062009
hydrolase activity	0.43684569040197	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	0.30903822799992	bayes_pls_golite062009
phosphoric ester hydrolase activity	0.18991962605066	bayes_pls_golite062009
phosphatase activity	0.18697224157516	bayes_pls_golite062009
phosphoprotein phosphatase activity	0.0814912829964198	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: