YRC Public Data Repository - Protein Structure Prediction

Protein:	prmt-4
Organism:	Caenorhabditis elegans
Length:	144 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for prmt-4.

Description	E-value	Query Range	Subject Range
MENG_STAAR - Demethylmenaquinone methyltransferase OS=Staphylococcus aureus (strain MRSA252) GN=menG PE=3 SV=1 gi\|227558277, gi... - gi\|227558277\|ref\|ZP_03988324.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Staphylococcu...	122.0	[0..3]	[143..15]
MENG_STAAB - Demethylmenaquinone methyltransferase OS=Staphylococcus aureus (strain bovine RF122 / ET3-1) GN=menG...	120.0	[0..3]	[143..15]
MENG_STAA1 - Demethylmenaquinone methyltransferase OS=Staphylococcus aureus (strain Mu3 / ATCC 700698) GN=menG PE... MENG_STAAW - Demethylmenaquinone methyltransferase OS=Staphylococcus aureus (strain MW2) GN=menG PE=3 SV=1 MENG_STAAE - Demethylmenaquinone methyltransferase OS=Staphylococcus aureus (strain Newman) GN=menG PE=3 SV=1 MENG_STAA9 - Demethylmenaquinone methyltransferase OS=Staphylococcus aureus (strain JH9) GN=menG PE=3 SV=1 gi\|269203096\|ref... - ubiquinone/menaquinone biosynthesis methyltransferase [Staphylococcus aureus subsp. aureus ED98] gi\|25304996 - pir\|\|G89925 menaquinone biosynthesis methyltransferase [imported] - Staphylococcus aureus (strain N3... MENG_STAAT - Demethylmenaquinone methyltransferase OS=Staphylococcus aureus (strain USA300 / TCH1516) GN=menG PE=... gi\|221140962 - gi\|221140962\|ref\|ZP_03565455.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Staphylococcu... MENG_STAAS - Demethylmenaquinone methyltransferase OS=Staphylococcus aureus (strain MSSA476) GN=menG PE=3 SV=1 gi\|221138325 - gi\|221138325\|ref\|ZP_03563127.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Staphylococcu... MENG_STAAM - Demethylmenaquinone methyltransferase OS=Staphylococcus aureus (strain Mu50 / ATCC 700699) GN=menG P... MENG_STAAN - Demethylmenaquinone methyltransferase OS=Staphylococcus aureus (strain N315) GN=menG PE=1 SV=1 gi\|251802063, gi... - gi\|251814398\|ref\|ZP_04828871.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Staphylococcu... gi\|253315978 - gi\|253315978\|ref\|ZP_04839191.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Staphylococcu... gi\|253732113, gi... - gi\|253732113\|ref\|ZP_04866278.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Staphylococcu... gi\|253728822, gi... - gi\|253733282\|ref\|ZP_04867447.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Staphylococcu... gi\|255006257 - gi\|255006257\|ref\|ZP_05144858.2\| ubiquinone/menaquinone biosynthesis methyltransferase [Staphylococcu... MENG_STAA2 - Demethylmenaquinone methyltransferase OS=Staphylococcus aureus (strain JH1) GN=menG PE=3 SV=1 MENG_STAAC - Demethylmenaquinone methyltransferase OS=Staphylococcus aureus (strain COL) GN=menG PE=3 SV=1	120.0	[0..3]	[143..15]
MENG_STAES - Demethylmenaquinone methyltransferase OS=Staphylococcus epidermidis (strain ATCC 12228) GN=menG PE=3... UBIE_STAEP - (Q8CSH9) Menaquinone biosynthesis methyltransferase ubiE (EC 2.1.1.-) MENG_STAEQ - Demethylmenaquinone methyltransferase OS=Staphylococcus epidermidis (strain ATCC 35984 / RP62A) GN=m...	120.0	[0..3]	[143..15]
gi\|88855943, gi\|... - gi\|88855943\|ref\|ZP_01130605.1\| ubiquinone/menaquinone biosynthesis methyltransferase [marine actinob...	119.0	[0..3]	[141..12]
MENG_MICLU - Demethylmenaquinone methyltransferase OS=Micrococcus luteus GN=menG PE=3 SV=1	118.0	[0..3]	[144..24]
gi\|47013898, gi\|... - gi\|47097727\|ref\|ZP_00235228.1\| 2-heptaprenyl-1,4-naphthoquinone methyltransferase [Listeria monocyto... gi\|126943708, gi... - gi\|254899372\|ref\|ZP_05259296.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Listeria mono... gi\|127765209, gi... - gi\|254912489\|ref\|ZP_05262501.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Listeria mono... gi\|133732157, gi... - gi\|254936816\|ref\|ZP_05268513.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Listeria mono...	118.0	[0..3]	[138..13]
UBIE_LISIN - Demethylmenaquinone methyltransferase OS=Listeria innocua GN=ubiE PE=3 SV=1 UBIE_LISMO - Demethylmenaquinone methyltransferase OS=Listeria monocytogenes GN=ubiE PE=3 SV=1 MENG_LISIN - Demethylmenaquinone methyltransferase OS=Listeria innocua serovar 6a (strain CLIP 11262) GN=menG PE=... gi\|47094454, gi\|... - gi\|47094454\|ref\|ZP_00232134.1\| 2-heptaprenyl-1,4-naphthoquinone methyltransferase [Listeria monocyto... UBIE_LISMC - Menaquinone biosynthesis methyltransferase ubiE OS=Listeria monocytogenes serotype 4b (strain Clip81... gi\|254825574 - gi\|254825574\|ref\|ZP_05230575.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Listeria mono... gi\|254852834 - gi\|254852834\|ref\|ZP_05242182.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Listeria mono... gi\|254877951 - gi\|254877951\|ref\|ZP_05250661.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Listeria mono... MENG_LISMC - Demethylmenaquinone methyltransferase OS=Listeria monocytogenes serotype 4b (strain CLIP80459) GN=me... MENG_LISMF - Demethylmenaquinone methyltransferase OS=Listeria monocytogenes serotype 4b (strain F2365) GN=menG P... gi\|254993470 - gi\|254993470\|ref\|ZP_05275660.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Listeria mono... MENG_LISMO - Demethylmenaquinone methyltransferase OS=Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / ... gi\|255521039 - gi\|255521039\|ref\|ZP_05388276.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Listeria mono... gi\|254831468, gi... - gi\|254831468\|ref\|ZP_05236123.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Listeria mono... gi\|153167788, gi... - gi\|153167788\|ref\|ZP_01927873.1\| 2-heptaprenyl-1,4-naphthoquinone methyltransferase [Listeria monocyt... gi\|254827184, gi... - gi\|254827184\|ref\|ZP_05231871.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Listeria mono... gi\|153202924, gi... - gi\|254931898\|ref\|ZP_05265257.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Listeria mono... gi\|224498619 - gi\|224498619\|ref\|ZP_03666968.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Listeria mono... gi\|224501270 - gi\|224501270\|ref\|ZP_03669577.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Listeria mono...	118.0	[0..3]	[138..13]
gi\|50950546, gi\|... - gi\|50954064\|ref\|YP_061352.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Leifsonia xyli s...	118.0	[0..1]	[141..17]
gi\|157759253 - gi\|157759253\|ref\|XP_001671970.1\| Hypothetical protein CBG10553 [Caenorhabditis briggsae AF16] gi\|39580933, gi\|... - gi\|39580933\|emb\|CAE65563.1\| Hypothetical protein CBG10553 [Caenorhabditis briggsae], gi\|187030956\|em...	118.0	[0..4]	[142..3]

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Predicted Domain #1

Region A:
Residues: [1-144]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSDFPTDPY STAQQKWLYQ DHLVLPTLEK LLKYNLKDKK VLDIGCGNGL NSTTFLQWGA  60
   61 RKVVGFDNSQ EMIENCKNLH KSSEQSSFHH LNVTDFQLDE KFHVATAVFV LQYVHDKEEL 120
  121 RKAIRLIWER KLRNGWFRLW MEDL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	24.0
Match:	1ve3A
Description:	Crystal structure of PH0226 protein from Pyrococcus horikoshii OT3
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.723277178398499	bayes_pls_golite062009
transferase activity	0.64512166557639	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	0.54403439349476	bayes_pls_golite062009
methyltransferase activity	0.54389223881989	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: