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View Structure Prediction Details

Protein: CE17126
Organism: Caenorhabditis elegans
Length: 543 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE17126.

Description E-value Query
Range
Subject
Range
gi|114609255 - gi|114609255|ref|XP_001167667.1| PREDICTED: protein tyrosine phosphatase, receptor type, K isoform 6...
391.0 [0..38] [543..715]

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Predicted Domain #1
Region A:
Residues: [1-93]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEKKEKKSVI QRVKRTLRQR SKSTDASSEQ KKGTKTVDDA EAPSKITRVK AAITNRTRSI  60
   61 GIKISISKEC NTTTSKGSSR ESDQKTKNSV LSS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.0
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [94-543]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VDMEEDPEAP VQTPDLMMIE IKKEELKEKK EKEKKDEEKR ERQEDRKEER KENKREDKKE  60
   61 EKKEEKKEEK KEVRKDCREN SVYFMERSDE KGVKKKHSKK HSKQKTKMWL GMPSALNFCN 120
  121 KNNDIQKIRE EFGFLDSLVC NKTTEAFEAN KVRNREGCPK IYDENRVQLN RPGHEDVNYI 180
  181 NASVITLTDV CRRMACVPAY VHLVVLYFVI FQFEHKLIVA QLPQMENESF VEDFWYMIYQ 240
  241 EQIHLVYLMV PDDKLKNTTT SLFNDENGGY QYTGKMFINN RRADVSGDPK EYTIEVLPEG 300
  301 NSDSVICQVH HHAPWKHLQQ PPKTLPIIKM IHQFLSEKQV QNAGVCVVSL FGCGRACSFI 360
  361 GALYAINQLN NGIEPNICEI MKNIKQQRPG GVESFAQYAS IYAIVFDYIA RKRGGKKAPV 420
  421 NKDINRFIDE LAEISPACSP TKVMPLSTEL 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 73.39794
Match: 2shpA
Description: Tyrosine phosphatase; Tyrosine phoshatase shp-2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.434026084000615 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 0.38379754974017 bayes_pls_golite062009
phosphoric ester hydrolase activity 0.379743522718551 bayes_pls_golite062009
phosphatase activity 0.37915439306018 bayes_pls_golite062009
protein binding 0.31534665043077 bayes_pls_golite062009
phosphoprotein phosphatase activity 0.0905316221038603 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle