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View Structure Prediction Details

Protein: egg-4
Organism: Caenorhabditis elegans
Length: 753 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for egg-4.

Description E-value Query
Range
Subject
Range
egg-5 - protein-tyrosine phosphatase status:Partially_confirmed UniProt:O61789 protein_id:AAC17031.1
602.0 [0..1] [753..1]

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Predicted Domain #1
Region A:
Residues: [1-664]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALNSEVMFR EQINAMRSQA GRKRATSLQS FCSGNTDDSS ADSTDNMDMM VDYPQQKGVS  60
   61 CMRARFNSES TLSKSFRKKV KKLAQKDRRS KERLNGNSEE DAIEVPRGAP STYAAPSKLR 120
  121 KSKALDCLVS EKPKDEGRRE DSGHGADIEM AKGHFNNVRM KVFAARTAMQ VEPALVMKTR 180
  181 KALEMKNAVL ENHQSPGAFS LHAAYKIAAS AESRVGSITP CNKKVTKEAM ANLIRSSYDD 240
  241 TEITQELLFS SKFDTKWKGR YTDIYMRRDE NGKKPKRPVN GQGWVMPLKS ICEKFGINST 300
  301 FFTNHRIDLK SARDQVLLMR LLSHDQTSTW ISDIHPEAVK NETMAEYLLR ELDASTMQKR 360
  361 VQAFKANVLA DRDRVRVAGQ FYNNIRIGKR MFGAARKAKY LSTIIGGMER RFEILENSVN 420
  421 HIPFTHSASD NNQEKCRNPR VHCKDSTRIA LQFPRGQYLG DFIHANRISG KPLFNEFIMT 480
  481 QAPMKNTVDD FWRMVWQEEV PYIVMLTSRK EPERCEYYWP KSPSDPAVTV PGGLRIENFG 540
  541 VYQAPDPLFR VTHLRLIGPD REERHVEHWQ GDVNNSSNMY SPLNILRLLR NASKPVVIHD 600
  601 HLGVSRAACL VAAEIAICSL LRGPTYKYPV QRAVQFLRQR RPFSIETPMQ YIFVHRLVAF 660
  661 FFRD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 136.0
Match: 2fh7A
Description: Crystal structure of the phosphatase domains of human PTP SIGMA
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [665-753]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VIGSAKELDV DYERWLQERS ERMFLDDLAA PIPGYRLLSP RADPDIVRMV GRPERPNYRR  60
   61 EAPDCVGEMP NKVATVDGIL SPAKSVFEF

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle