YRC Public Data Repository - Protein Structure Prediction

Protein:	emr-1
Organism:	Caenorhabditis elegans
Length:	166 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for emr-1.

Description	E-value	Query Range	Subject Range
LEMD1 - LEM domain containing 1	151.0	[0..1]	[150..2]
gi\|114572111 - gi\|114572111\|ref\|XP_001161560.1\| PREDICTED: LEM domain containing 1 isoform 4 [Pan troglodytes]	150.0	[0..1]	[150..2]
gi\|18495785 - gi\|18495785\|emb\|CAC86206.1\| lamina-associted protein 2 beta [Danio rerio]	148.0	[0..1]	[162..93]
gi\|39589435, gi\|... - gi\|39589435\|emb\|CAE74464.1\| Hypothetical protein CBG22210 [Caenorhabditis briggsae], gi\|187022078\|em... gi\|157745195 - gi\|157745195\|ref\|XP_001667694.1\| Hypothetical protein CBG22210 [Caenorhabditis briggsae AF16]	141.0	[0..1]	[150..1]
gi\|109132796 - gi\|109132796\|ref\|XP_001090376.1\| PREDICTED: emerin (Emery-Dreifuss muscular dystrophy) [Macaca mulat...	141.0	[0..2]	[132..3]
gi\|29335751, gi\|... - gi\|29335751\|dbj\|BAC66442.1\| nuclear membrane protein XMAN1 [Xenopus laevis], gi\|148225084\|ref\|NP_001...	141.0	[0..1]	[129..1]
EMD_MOUSE - Emerin OS=Mus musculus GN=Emd PE=1 SV=1	139.0	[0..2]	[132..3]

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Predicted Domain #1

Region A:
Residues: [1-77]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDVSQLTDAE LRDSLKSHGV SVGPIVATTR KLYEKKLIKL SDGSINNQSN LNDSQFNEDS  60
   61 LIISSSPKKS PPQRVFQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	11.522879
Match:	1jeiA
Description:	Inner nuclear membrane protein emerin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	0.144074953244994	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [78-166]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NVSAATAAAT TSPESDSDDC EESMRYLTEE EMAADRASAR QAQSNKGGFL GSTITFTILF  60
   61 VFIAVFAYFL IENAEQLKLV AETNPEDTI

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: