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View Structure Prediction Details

Protein: fum-1
Organism: Caenorhabditis elegans
Length: 501 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for fum-1.

Description E-value Query
Range
Subject
Range
gi|157776283 - gi|157776283|ref|XP_001666207.1| hypothetical protein CBG09180 [Caenorhabditis briggsae AF16]
gi|39582033, gi|... - gi|39582033|emb|CAE64464.1| Hypothetical protein CBG09180 [Caenorhabditis briggsae], gi|187032082|em...
586.0 [0..11] [501..1]

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Predicted Domain #1
Region A:
Residues: [1-501]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSAVSMLQGE MLARGGAVIA RGASLATARN FSRTTVPMAK IRKERDTFGE LEVPADKYYG  60
   61 AQTARSQMNF KIGGPEERMP IPVIHAFGIL KKAAALVNTE FGLDKKLADA ISQAADEVVD 120
  121 GKLDEHFPLV TWQTGSGTQS NMNVNEVISN RAIEILGGEL GSKKPVHPND HVNMSQSSND 180
  181 TFPTAMHIAV GREVNSRLLP ALKKLRTALH NKAEEFKDII KIGRTHTQDA VPLTLGQEFS 240
  241 AYVTQLDNSI ARVESTLPRL YQLAAGGTAV GTGLNTRKGF AEKVAATVSE LTGLPFVTAP 300
  301 NKFEALAAHD ALVEVHGALN TVAVSFMKIG NDIRFLGSGP RCGLGELSLP ENEPGSSIMP 360
  361 GKVNPTQCEA ITMVAAQVMG NQVAVSVGGS NGHFELNVFK PLIVRNVLQS TRLLADSAVS 420
  421 FTDHCVDGIV ANKDNIAKIM RESLMLVTAL NPHIGYDNAA KIAKTAHKNG TTLVQEAVKL 480
  481 GILTEEQFAQ WVKPENMLGP K

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 157.0
Match: 1yfmA
Description: RECOMBINANT YEAST FUMARASE
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
fumarate hydratase activity 4.22589182982073 bayes_pls_golite062009
catalytic activity 2.51282259572665 bayes_pls_golite062009
lyase activity 2.31268471569846 bayes_pls_golite062009
carbon-nitrogen lyase activity 2.2046475419807 bayes_pls_golite062009
histidine ammonia-lyase activity 0.948129236753279 bayes_pls_golite062009
amidine-lyase activity 0.901614580251298 bayes_pls_golite062009
binding 0.854855116369286 bayes_pls_golite062009
argininosuccinate lyase activity 0.617974375213548 bayes_pls_golite062009
ammonia-lyase activity 0.491229595527877 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle