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View Structure Prediction Details

Protein: acr-17
Organism: Caenorhabditis elegans
Length: 446 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for acr-17.

Description E-value Query
Range
Subject
Range
gi|2764509 - gi|2764509|emb|CAA04053.1| nicotinic acetylcholine receptor, alpha2 subunit [Locusta migratoria]
379.0 [0..21] [444..1]

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Predicted Domain #1
Region A:
Residues: [1-345]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MISFQLLLRI VVLHFLMGLA MAQQKQLIKY LFRDYHKELR PVKDESSGPT NVTVQLYFKQ  60
   61 IQKVHENDQI ITLYCWIEEY WQDEFLTWNP SDFGNIKSLH VPSEMIWKPD LLVYNNANMN 120
  121 IKENEMQTNV QIEHTGKISL FRAIITDITC DLQMEKFPYD QQICFIMLAS WSYDGSQIML 180
  181 NTAEQPTEAP LDIKNTTNLA ILNHYIPNME WKLVDFRYRN NLKYYDCCPN PYPDISYFFA 240
  241 IKRNPSYYLF TLIIPSAFIT IVTVIGFFTP HSSTGENTEK VSLGVTALLS LAIILMMVSD 300
  301 KLPATSNSVP LLGQYYIGLI FIMFLATYCT TFTLGIQMQG NAGRP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 75.0
Match: 2bg9A
Description: Refined structure of the nicotinic acetylcholine receptor at 4A resolution.
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [346-446]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ITRRLRSFLL SIRMNRNSFV QWFFGRELMN TQESIKMRLK KYHNKTASLI EQESIDSSKL  60
   61 LDPAMYNVVV DVLSSVQSIR QDLTSQEHLK RIRKEWQMLA R

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 38.39794
Match: 1oedA
Description: Acetylcholine receptor protein, alpha chain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle