YRC Public Data Repository - Protein Structure Prediction

Protein:	smn-1
Organism:	Caenorhabditis elegans
Length:	197 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for smn-1.

Description	E-value	Query Range	Subject Range
smn-1 - Human muscular atrophy protein like status:Confirmed UniProt:Q9U758 protein_id:CAC42273.1	260.0	[0..1]	[197..11]
SMN_BOVIN - Survival motor neuron protein OS=Bos taurus GN=SMN1 PE=2 SV=2	224.0	[0..2]	[193..25]
gi\|187040106, gi... - gi\|39579756\|emb\|CAE56707.1\| Hypothetical protein CBG24493 [Caenorhabditis briggsae], gi\|187040106\|em...	220.0	[0..1]	[192..11]
gi\|13259512, gi\|... - gi\|169167330\|ref\|XP_001713783.1\| PREDICTED: hypothetical protein isoform 2 [Homo sapiens], gi\|169167... gi\|114599811 - gi\|114599811\|ref\|XP_001156259.1\| PREDICTED: survival of motor neuron 1, telomeric isoform 3 [Pan tro...	218.0	[0..2]	[193..29]
SMN_PONAB - Survival motor neuron protein OS=Pongo abelii GN=SMN1 PE=2 SV=1 gi\|55726440 - gi\|55726440\|emb\|CAH89989.1\| hypothetical protein [Pongo abelii]	215.0	[0..2]	[193..29]
ENSMMUG000000202... - null, null SMN_MACFA - Survival motor neuron protein OS=Macaca fascicularis GN=SMN1 PE=2 SV=1	214.0	[0..2]	[193..29]
gi\|114599807 - gi\|114599807\|ref\|XP_001156488.1\| PREDICTED: survival of motor neuron 1, telomeric isoform 7 [Pan tro...	214.0	[0..2]	[193..29]
gi\|31075799 - gi\|31075799\|gb\|AAP42462.1\| survival motor neuron [Canis familiaris]	213.0	[0..2]	[193..20]

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Predicted Domain #1

Region A:
Residues: [1-197]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEVDDVWDDT ELIKMYDESL QEISKNETSA KITSRKFKGE DGKMYTWKVG GKCMAPYEEN  60
   61 GEVTDYPATI DTIGGADNLE VGVTFIYYGG QAVVQMKDLW LNEEAIADAV KAENDLQKTK 120
  121 KTSTVNSVAH SNSKSTSSAP NTSMPFPSFA PPVPPNIIAM APVNQKEAMN SMLMSWYMSG 180
  181 YHTGYYQALA DQKNVQN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	24.39794
Match:	1g5vA
Description:	Survival motor neuron protein 1, smn
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	1.50121748882076	bayes_pls_golite062009
protein binding	0.95084028886111	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: