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View Structure Prediction Details

Protein: CE07817
Organism: Caenorhabditis elegans
Length: 342 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE07817.

Description E-value Query
Range
Subject
Range
gi|73963740 - gi|73963740|ref|XP_537523.2| PREDICTED: similar to Activator of 90 kDa heat shock protein ATPase hom...
396.0 [0..1] [342..1]

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Predicted Domain #1
Region A:
Residues: [1-196]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKWGEGDPR WIVEERADAT NVNNWHWSEK NATPWSLNRL RELLTGFSSE DGPIVVTIDE  60
   61 IKKIDGEATA NNRKAKLIFL FEWVIEGTFI ARVSGSEDEY KGTFDIPNLS DENDASEVDV 120
  121 NSSLSGNGPM AHQIRQVLNK SFIAKIQDVM GIYIRELKEE FSKGLILPTD KVKPQVVTTG 180
  181 KTSVVDKRQF QNTVVA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 46.69897
Match: 1usvB
Description: The Structure of the complex between Aha1 and HSP90
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
chaperone binding 2.83340109651263 bayes_pls_golite062009
ATPase regulator activity 2.31076586548557 bayes_pls_golite062009
ATPase activator activity 1.99816875782377 bayes_pls_golite062009
binding 1.41211290001748 bayes_pls_golite062009
protein binding 1.12549021331477 bayes_pls_golite062009
heat shock protein binding 0.87871487226722 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [197-342]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EKDASTSGNE VFSTKEVSTS DTYKATPDRV FEALTETQFV RGWTNNSIGE WNFKEGGSFA  60
   61 LFGENVTGTF EKIEPNKEIV KKWRLKKYPN NHHATIHFQL KDTGSGTDIK IIAKDVPTHL 120
  121 AEETQQGLDR YYLSSIGRTF GFSQRM

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 34.221849
Match: 1x53A
Description: The solution structure of the C-terminal domain of human Activator of 90 kDa heat shock protein ATPase homolog 1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.800494322693462 bayes_pls_golite062009
protein binding 0.186935278553638 bayes_pls_golite062009
catalytic activity 0.0116392906163881 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle