YRC Public Data Repository - Protein Structure Prediction

Protein:	CE05705
Organism:	Caenorhabditis elegans
Length:	188 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE05705.

Description	E-value	Query Range	Subject Range
gi\|157762414 - gi\|157762414\|ref\|XP_001673549.1\| Hypothetical protein CBG23457 [Caenorhabditis briggsae AF16] TOM20_CAEBR - Mitochondrial import receptor subunit TOM20 homolog OS=Caenorhabditis briggsae GN=tomm-20 PE=3 SV=1	241.0	[0..1]	[188..1]
TOM20_MOUSE - Mitochondrial import receptor subunit TOM20 homolog OS=Mus musculus GN=Tomm20 PE=1 SV=1 TOM20_RAT - Mitochondrial import receptor subunit TOM20 homolog OS=Rattus norvegicus GN=Tomm20 PE=1 SV=2	210.0	[0..8]	[159..1]
gi\|123980398, gi... - gi\|168274282\|dbj\|BAG09561.1\| translocase of outer mitochondrial membrane 20 homolog [synthetic const... TOM20_PONAB - Mitochondrial import receptor subunit TOM20 homolog OS=Pongo abelii GN=TOMM20 PE=2 SV=1 TOMM20 - translocase of outer mitochondrial membrane 20 homolog (yeast) tr\|M3X685\|M3X685... - Translocase of outer mitochondrial membrane 20 OS=Felis catus GN=TOMM20 PE=3 SV=1 tr\|G3GWY3\|G3GWY3... - Mitochondrial import receptor subunit TOM20-like OS=Cricetulus griseus GN=I79_002269 PE=3 SV=1 TOM20_PONPY - Mitochondrial import receptor subunit TOM20 homolog - Pongo pygmaeus (Orangutan) gi\|194042565 - gi\|194042565\|ref\|XP_001926970.1\| PREDICTED: similar to Mitochondrial import receptor subunit TOM20 h... ENSCJAT00000035423 - null tr\|G1TX78\|G1TX78... - pep:novel chromosome:oryCun2:16:33118276:33133165:1 gene:ENSOCUG00000021470 transcript:ENSOCUT000000... gi\|109019950 - gi\|109019950\|ref\|XP_001102478.1\| PREDICTED: translocase of outer mitochondrial membrane 20 homolog (... TOM20_BOVIN - Mitochondrial import receptor subunit TOM20 homolog OS=Bos taurus GN=TOMM20 PE=2 SV=1 gi\|114573267, gi... - gi\|114573269\|ref\|XP_001153572.1\| PREDICTED: translocase of outer mitochondrial membrane 20 homolog i...	209.0	[0..8]	[159..1]
gi\|1838935 - gi\|1838935\|dbj\|BAA09714.1\| mitochondrial precursor receptor [Rattus sp.]	209.0	[0..8]	[159..1]
gi\|76676674 - gi\|76676674\|ref\|XP_870365.1\| PREDICTED: similar to Mitochondrial import receptor subunit TOM20 homol...	208.0	[0..8]	[159..1]
TOM20_RAT, OM20_RAT - Mitochondrial import receptor subunit TOM20 homolog - Rattus norvegicus (Rat), (Q62760) Mitochondria...	207.0	[0..8]	[159..1]
gi\|109085461 - gi\|109085461\|ref\|XP_001094304.1\| PREDICTED: translocase of outer mitochondrial membrane 20 homolog (...	204.0	[0..8]	[159..1]
gi\|49069072, gi\|... - gi\|71005382\|ref\|XP_757357.1\| hypothetical protein UM01210.1 [Ustilago maydis 521], ref\|XP_398825.1\| ...	200.0	[0..8]	[185..1]
gi\|50797812 - gi\|50797812\|ref\|XP_423972.1\| PREDICTED: similar to Mitochondrial import receptor subunit TOM20 homol...	198.0	[0..8]	[159..74]

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Predicted Domain #1

Region A:
Residues: [1-188]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDTILGFNK SNVVLAAGIA GAAFLGYCIY FDHKRINAPD YKDKIRQKRR AQAGAGGMAP  60
   61 RRPAAAGNDA APDVTDPSQM QRFFLQEVQL GEELMAAGNV DEGAVHIANA VMLCGESQQL 120
  121 LSIFQQTLSE DQFRAVVQQL PSTRERLAEM FGAKADEAEN EPPMVQYLGD GPPPAQIQEL 180
  181 IDDTDDLE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	28.30103
Match:	1om2A
Description:	Mitochondrial import receptor subunit Tom20
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
P-P-bond-hydrolysis-driven protein transmembrane transporter activity	3.40898729129243	bayes_pls_golite062009
macromolecule transmembrane transporter activity	3.40898729129243	bayes_pls_golite062009
protein transmembrane transporter activity	2.85488085984023	bayes_pls_golite062009
protein transporter activity	2.05250883327513	bayes_pls_golite062009
transporter activity	1.79559401386194	bayes_pls_golite062009
transmembrane transporter activity	1.6303525042646	bayes_pls_golite062009
binding	1.61734984949766	bayes_pls_golite062009
substrate-specific transporter activity	1.49267876312697	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	1.3436996680931	bayes_pls_golite062009
primary active transmembrane transporter activity	1.0671316259706	bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity	1.06141451496527	bayes_pls_golite062009
active transmembrane transporter activity	1.01882616059722	bayes_pls_golite062009
protein binding	0.798129451991244	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: