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View Structure Prediction Details

Protein: CE05602
Organism: Caenorhabditis elegans
Length: 435 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE05602.

Description E-value Query
Range
Subject
Range
gi|206600, gi|14... - gi|206600|gb|AAA42024.1| cystathionine beta-synthase, gi|158186659|ref|NP_036654.2| cystathionine-be...
331.0 [0..16] [430..40]

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Predicted Domain #1
Region A:
Residues: [1-435]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKLLLLALFL SISASCLAED ITKISESRIP NEDAVPDYEA KWRLGAIQKL WNERRKMGHT  60
   61 PMTKFSPPGF PNADIFFKNE TATATRTLKH RFAWALLLWA ITEGKVTSKT SAVYDSTSGN 120
  121 TGSAEAYMCT LVNVPYYAVV ADNLEKEKVK QIESFGGKII KVPVALRNAK AKEFADKNHG 180
  181 FYMNQFGNAE KAEEFHESGD FYFESTNVYH EIIVQLKKDK EQIVKIPDYF VHSAGTGGTI 240
  241 SSVGRYVARY GAPTKVVLSD SQYSLFYDYV IGHKFTNQSG AGIWTPPGIA GIGYGYDIEP 300
  301 VWYGETTSLT RNVIHEAMKM PDIASVATMR ILDEKGYNVG PSTSLNFLVS LYKAYQNKAR 360
  361 KSAIKHRLTI VTLACDPGDF YRSTYLNNEW VEKSFKKFGG VMGMECWKKL IQESIDTGSD 420
  421 FYSKGLTMCP GAFKV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 86.522879
Match: 1jbqA
Description: Cystathionine beta-synthase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
cysteine synthase activity 5.18562032111987 bayes_pls_golite062009
catalytic activity 2.38994231321972 bayes_pls_golite062009
lyase activity 1.87743897464083 bayes_pls_golite062009
cystathionine beta-synthase activity 1.4517088142802 bayes_pls_golite062009
tryptophan synthase activity 1.04832999357666 bayes_pls_golite062009
carbon-oxygen lyase activity 0.923824749425553 bayes_pls_golite062009
threonine synthase activity 0.727838845253199 bayes_pls_golite062009
ammonia-lyase activity 0.476674617721478 bayes_pls_golite062009
L-threonine ammonia-lyase activity 0.37325071016009 bayes_pls_golite062009
carbon-nitrogen lyase activity 0.249761226675912 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle