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View Structure Prediction Details

Protein: unc-112
Organism: Caenorhabditis elegans
Length: 720 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for unc-112.

Description E-value Query
Range
Subject
Range
gi|39589851, gi|... - gi|39589851|emb|CAE60849.1| Hypothetical protein CBG04558 [Caenorhabditis briggsae], gi|187035353|em...
gi|157765036 - gi|157765036|ref|XP_001674861.1| Hypothetical protein CBG04558 [Caenorhabditis briggsae AF16]
647.0 [0..1] [720..1]

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Predicted Domain #1
Region A:
Residues: [1-228]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAHLVEGTSI IDGKWQLPIL VTDLNIQRSI SVLGNLNVGG LMLELVSECD VERDWSDHAL  60
   61 WWPEKRRWLQ HTRSTLDQNG ITAETQLEFT PMHKEARIQL PDMQMIDARV DFSVNSFKAT 120
  121 KKLCRDLGIR YSEELSLKRY IPPEDLRRGT SDADNMNGPL SMRPGEESVG PMTLRKAAPI 180
  181 FASQSNLDMR RRGQSPALSQ SGHIFNAHEM GTLPRHGTLP RGVSPSPG

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.25
Match: 1z2mA
Description: Crystal Structure of ISG15, the Interferon-Induced Ubiquitin Cross Reactive Protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
cytoskeletal protein binding 3.02426833898488 bayes_pls_golite062009
binding 2.13150871371358 bayes_pls_golite062009
tubulin binding 1.89536452834658 bayes_pls_golite062009
protein binding 1.75262085947538 bayes_pls_golite062009
microtubule binding 1.5556420903187 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [229-412]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AYNDTMRRTP IMPSISFSEG LENEQFDDAL IHSPRLAPSR DTPVFRPQNY VEKAAINRGW  60
   61 LDSSRSLMEQ GIFEGDIILL RFKFMNFFDL NPKYDPVRIN QLYEQAKWSI LLDEFDHTEE 120
  121 EATLFAALQL QATLQRDSPE PEENNKDDVD ILLDELEQNL DAAALNRRSD LTQVPELADY 180
  181 LKYM

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 11.0
Match: 2j0kA
Description: No description for 2j0kA was found.

Predicted Domain #3
Region A:
Residues: [413-570]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KPKKLAAFKG FKRAFFSFRD LYLSYHQSSS DVNSAPLGHF SLKGCEVSQD VSVGQQKYHI  60
   61 KLLLPTAEGM IDFILKCDSE HQYARWMAAC RLASRGKSMA DSSYQQEVES IKNLLKMQSG 120
  121 NGNENGNSNT ASRKAAAVKL PNDFNVDEYI SSKYVRRA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 25.39794
Match: 2ys3A
Description: No description for 2ys3A was found.

Predicted Domain #4
Region A:
Residues: [571-720]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RSKQQIQQRV SDAHGNVRQL TATEAKLQYI RAWQALPEHG IHYFIVRFRN ARKAELVAVA  60
   61 VNRLAKLNMD NGESLKTWRF ANMKKWHVNW EIRHLKIQFE DEDIEFKPLS ADCKVVHEFI 120
  121 GGYIFLSMRS KEHSQNLDEE LFHKLTGGWA 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 34.221849
Match: 1y19B
Description: Structural basis for phosphatidylinositol phosphate kinase type I-gamma binding to talin at focal adhesions
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
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