YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: unc-18
Organism: Caenorhabditis elegans
Length: 673 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for unc-18.

Description E-value Query
Range
Subject
Range
gi|157770600 - gi|157770600|ref|XP_001677120.1| Hypothetical protein CBG16760 [Caenorhabditis briggsae AF16]
gi|39594149, gi|... - gi|39594149|emb|CAE70259.1| Hypothetical protein CBG16760 [Caenorhabditis briggsae], gi|187026176|em...
573.0 [0..85] [673..3]

Back

Predicted Domain #1
Region A:
Residues: [1-79]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQNVKHSYLA CSSSSCCQFF SLFLSLCHAE HQIQTLSPSF AYTLLIFALL VSDKSEIALL  60
   61 SRHTHTYIFL PISSVHPSL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [80-673]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ELLPFVVFMH MRKLLNDVIR PLKKGDGRSA WNVLIVDTLA MRMLSSCCKM HNIMEEGITI  60
   61 VEDLNKRREP LPTLEAIYLI APTAESIDKL IQDYCARNLY KCAHVFFTEA CSDQLFSTLS 120
  121 KSAAARFIKT LKEINIAFTP YESQVFNLDS PDTFFLYYNA QKQGGLTSNL ERIAEQIATV 180
  181 CATLGEYPSL RYRADFERNV ELGHLVEQKL DAYKADDPSM GEGADKARSQ LIIIDRGYDA 240
  241 ITPLLHELTL QAMCYDLLGI ENDVYKYETG GSDENLEKEV LLDENDDLWV EMRHKHIAVV 300
  301 SQEVTKNLKK FSESKGNKGT MDSKSIKDLS MLIKRMPQHK KELNKFSTHI SLAEECMKQY 360
  361 QQGVDKLCKV EQDLSTGIDA EGERVRDAMK LMVPLLIDPA VRCEDRLRLI LLYILSKNGI 420
  421 TDENLNKLLQ HANISMADKE TITNAAYLGL NIVTDTGRKK TWTPTKKERP HEQVYQSSRW 480
  481 VPVIKDIIED AIDERLDTKH FPFLAGRQVN QGYRAPASAR YGQWHKERGQ QSNYRSGPRL 540
  541 IIYIIGGVTF SEMRACYEVT AARKPWEVVI GSDRIITPDK FLTNLRDLNK PRDI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 159.0
Match: 1dn1A
Description: Neuronal Sec1, NSec1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
SNARE binding 4.56428593085019 bayes_pls_golite062009
syntaxin binding 3.46044132736061 bayes_pls_golite062009
binding 2.7837022903231 bayes_pls_golite062009
protein binding 2.77285532000616 bayes_pls_golite062009
syntaxin-1 binding 0.269372794919901 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle