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View Structure Prediction Details

Protein: czw-1
Organism: Caenorhabditis elegans
Length: 778 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for czw-1.

Description E-value Query
Range
Subject
Range
gi|114640374 - gi|114640374|ref|XP_508761.2| PREDICTED: centromere/kinetochore protein zw10 [Pan troglodytes]
ZW10 - ZW10, kinetochore associated, homolog (Drosophila)
768.0 [0..2] [778..18]

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Predicted Domain #1
Region A:
Residues: [1-246]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASSEGSYRD LEKKLKNGLT SISQDIVDKY GNLKVSLNVN ATAKLIFDRL ENLEDIAEMS  60
   61 TRNLSNLIDQ TAKDSPEMLA EIKSQAQSCE NLVEFLQSMK NVEEQLIIMR SKTTNRVEWG 120
  121 TAILACKDFL NDTNMLLEGI GRDGFDMSVP LKHFAAEYSV LSYNCRYQLS ADYERAMNVP 180
  181 KLSKQKCGDR TNVSFSVFNV GSVEDQKMLN ETLSAMNMIG QLPERLDAWK IVILNVFCEA 240
  241 IVASRD

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 0.974
Match: 1c1gA
Description: Tropomyosin
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [247-455]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GVDVYIVDNP TPDQTRFLIN QKPRGKKDKT IDVAKVLESM EVFFTKLHSV LHSHELLDAT  60
   61 GKTFTSMIGS VIEEQLITMI LKDVIAIAAP VTETADEDQE MFINLLQIGE VFVERMKELG 120
  121 FFSQKAKLLF TLDTDTIFVT RRCFAIVSKA NKLINETYDK LVTVGVDDSA IKDIDLLAKA 180
  181 HTHAEHFAKE YGKDLGRLWS HNEDSQFPS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [456-591]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FFAFQKCTVS ESTINFVNLL RDNVKAAFAC EDEGARAKLA LTAENIVRLY VILTPRKHAE  60
   61 LFSSIPNMAA IFYNNCHYIS HCIMTMSFEA SGDNQKTLLE PLLLDSVIRL RTVAADCMEK 120
  121 TLTRCRREMT AYLEDH

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [592-650]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SIFEHLPASY KTTKNTFAAA EEMSESADIL VPREEPKIIK CLAACLLHIR LIAKNLREP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [651-778]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LTEVVYCKVI GSLVSFLLDS LVRHVVTTSD FRENDANVMA DVFKRLLEVV ANIVAYKEQT  60
   61 KVTDFCAREY FRLNEIVFVL GNRMQDIEHR WFNAKGPMAE HLSRSEVVGL IKALFADSQH 120
  121 RSDLIARL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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