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View Structure Prediction Details

Protein: CE04132
Organism: Caenorhabditis elegans
Length: 364 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE04132.

Description E-value Query
Range
Subject
Range
gi|85829783, gi|... - gi|86143740|ref|ZP_01062116.1| 4-hydroxyphenylpyruvate dioxygenase [Flavobacterium sp. MED217], gi|8...
gi|85829783, gi|... - gi|86143740|ref|ZP_01062116.1| 4-hydroxyphenylpyruvate dioxygenase [Flavobacterium sp. MED217], gi|8...
311.0 [0..3] [363..24]

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Predicted Domain #1
Region A:
Residues: [1-364]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGSISAIHHI EFIVSNALQS AYWYCSGFGF EKFAEKITDE STSIALRNGT ARVIITSYNS  60
   61 QNIYTDQLIK HGDFIKDVSF RVDNLDAVLQ NLVENDIKVI QQSEVSTKDG LVRTATLLSE 120
  121 GGDVTHTLFE LGEFKGNFLP FFTPISNFEL FENIEKMPAI LMDHVVQNYP IGEMEAAADW 180
  181 YFKTMRLKRF WSVDDKVATS EFSAMTAWLL VNDDHTVQVT LAEGVKGRKG KSQIEEFINY 240
  241 HGGSGVQHFA LLVEDIISAV QIMKSRSVEF LTIPSQYYDN LEERLSKTNL IVKEDLKMIR 300
  301 ELNILMDFDE NGYLLQIFSK PLQDRPTLFI EIIQRANFKG FGAGNFKALF DAVEREQEKR 360
  361 GTLF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 81.69897
Match: 1sqiA
Description: Structural basis for inhibitor selectivity revealed by crystal structures of plant and mammalian 4-hydroxyphenylpyruvate dioxygenases
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
4-hydroxyphenylpyruvate dioxygenase activity 5.55625076505342 bayes_pls_golite062009
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 2.26788314282577 bayes_pls_golite062009
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 2.21815619779247 bayes_pls_golite062009
catalytic activity 1.21778090213032 bayes_pls_golite062009
binding 1.0574905568754 bayes_pls_golite062009
dioxygenase activity 0.768140787640544 bayes_pls_golite062009
protein binding 0.18929451652439 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle