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View Structure Prediction Details

Protein: CE03547
Organism: Caenorhabditis elegans
Length: 444 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE03547.

Description E-value Query
Range
Subject
Range
gi|23092863, gi|... - gi|24656434|ref|NP_647768.2| CG1869-PA [Drosophila melanogaster], gi|23092863|gb|AAF47714.2| CG1869-...
321.0 [0..76] [442..116]

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Predicted Domain #1
Region A:
Residues: [1-79]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNVIAFSCRK DSGQEPSQSR WRPYLKYIII VAVFLIVVAI ATVTIVLIAN RVDGSANTST  60
   61 VPNVSSTVAK STITTRAPP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [80-444]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VCNKRIIGYY FATQTSVITR DQVSKLTHAV FAFVNMTSDG HLQIDGDLAK NRFTNLIEIA  60
   61 KQQTPQVKVM ISIGGNDNSN NFKPGLSSPD RKKLFINSTV SFLQTYDIDG VDLYWKWPGK 120
  121 TSKDIYSQFI NDLRYSLQRQ KRNYIMSIVL PPPDMGANYE AGIDIENIFD NVDFLNIFTM 180
  181 GYFGPWQNDA GMITGAASQL FNGVNGVPGR KTYNIHHSTE RYVCKTGQSD KYNIAIPFYT 240
  241 MLWKHVKGPV NPPNIEIYRN ATFQGGVVGE TSMSRKLVQE EGYDFSNPTY NPEIRAAFKY 300
  301 NATTETFLTF ETNDTIAAKI DYVKDRILGG VWIWAVDMDD DSNNLLNLVK FTGYCTVGNL 360
  361 TLYNC

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 84.0
Match: 1wawA
Description: Specificity and affnity of natural product cyclopentapeptide inhibitor Argadin against human chitinase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
chitinase activity 6.40555694403866 bayes_pls_golite062009
hydrolase activity, hydrolyzing O-glycosyl compounds 1.91170236789651 bayes_pls_golite062009
amylase activity 1.38959979746158 bayes_pls_golite062009
hydrolase activity, acting on glycosyl bonds 1.34796838721403 bayes_pls_golite062009
chitin binding 1.29046765706168 bayes_pls_golite062009
growth factor activity 0.803631304661827 bayes_pls_golite062009
receptor binding 0.607116029438976 bayes_pls_golite062009
catalytic activity 0.534516847146079 bayes_pls_golite062009
glucosidase activity 0.528679164808812 bayes_pls_golite062009
carbohydrate binding 0.4998423581103 bayes_pls_golite062009
binding 0.459434776404249 bayes_pls_golite062009
hydrolase activity 0.391743039933741 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle