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View Structure Prediction Details

Protein: din-1
Organism: Caenorhabditis elegans
Length: 567 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for din-1.

Description E-value Query
Range
Subject
Range
gi|25395621 - gi|25395621|pir||E88320 protein F07A11.6 [imported] - Caenorhabditis elegans
239.0 [0..1] [567..2172]

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Predicted Domain #1
Region A:
Residues: [1-153]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSAEEAATVM AVASSDPNPP ATSTVDLAAM LQQLQAAQAA QAAQQVPVVT TASTPNPLSN  60
   61 LETLLSTASL ANLATGGALN PLSMLALTSS LNQSSPVYQG IARVLLTMNM GQMLATHQTS 120
  121 ELLATMNQQE TLMALLAARN GLPFAMPQQN QQP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [154-321]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QMPAQGGFAI PTVLPHMSLK RNAKDQLSVG GVSDRKKSCP LHAMIGQGQQ PPPPQQPMQA  60
   61 VAPAPPRSPS PPRKSMFENL PPEMKEKNEM FRKEILRRLD IILLEELGAE DEEDQKPDLK 120
  121 QIPTSEEDTD DSKADSMGAE GSAFRRILSR SSTMGNNSGS PSASGTTS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [322-567]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSTSSSISSG PDSPPLEGEP LNSEFMDMLT EVAQKHREQS NTDALSAKIV DEQSFSQHFP  60
   61 MVWTGRLALK STEAMINLHL INGSETFLND VLGRQVTEEN PRRDSVKILQ RLRLDNGQVE 120
  121 HIYRILTNPE YACCLALSSV NNIENLKEND TNLKSHFIDY LINKKIAGIS SLGEVETKFK 180
  181 SARVHVFAPG EIVNRYLSEL ATSLHDYLQN TDTRYLLIVF TNDKADPNMT GPPSVASLAV 240
  241 PPVSST

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 50.30103
Match: 1ow1A
Description: Crystal structure of the SPOC domain of the human transcriptional corepressor, SHARP.
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle