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View Structure Prediction Details

Protein: cfim-2
Organism: Caenorhabditis elegans
Length: 489 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for cfim-2.

Description E-value Query
Range
Subject
Range
gi|73976797 - gi|73976797|ref|XP_857696.1| PREDICTED: similar to poly(A) binding protein, cytoplasmic 4 isoform 1 ...
308.0 [0..2] [470..123]

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Predicted Domain #1
Region A:
Residues: [1-169]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAELDEAALL GDGNEQHDGP IDENALLDGK ELKEEDIDDL YDEAIAPTNS TESAKPVSPT  60
   61 ITTVTAPTAG IGAKPATSSE GRKYCCYVGN LLWYTTDADL LKALQSTGLA RSQFADMKFF 120
  121 ENRTNGQSKG YALLVLNSDA AVKQTMEILP TKTIHGQSPT VLSYNKTNQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 33.154902
Match: 1po6A
Description: Crystal Structure of UP1 Complexed With d(TAGG(6MI)TTAGGG): A Human Telomeric Repeat Containing 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine (6MI)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.10590295737522 bayes_pls_golite062009
nucleic acid binding 1.43479844212501 bayes_pls_golite062009
RNA binding 0.426544317458995 bayes_pls_golite062009
protein binding 0.303849616374798 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [170-370]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AKLEDAQAKN QTRPDVKKKG FEEGCVNMGT IRIGAGGQTG RTGTSVSGRS GPPPLMMQQV  60
   61 RPTPLMSQPT SLPSNLNQAP QMRLQINGQQ VPLMNRAPVP QQTMLGNGPL GGMNQQIQQQ 120
  121 PQMMMGQQVR PMMQTSMGIQ PMMGMNAPPP MNNQFQNRPP QLGSMGVQPL MQMNTAMRPP 180
  181 INGLPPVHVN PQMFPGLQGT V

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.221849
Match: 1m2vB
Description: Sec24
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [371-489]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LSDAEFEDVM TRNQTVSSSA IARAITDASV GDIKGASETI LTAIQLIKNS RIGHDERCRQ  60
   61 LVYGLEHTLK GLESKGYSSR SKSHRDRSRS RERDRKRRRR SRTRSRSYSR SPSPRRRRY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.69897
Match: 1g9lA
Description: poly(A) binding protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.22356908090969 bayes_pls_golite062009
nucleic acid binding 0.30263065494542 bayes_pls_golite062009
protein binding 0.0377709835534661 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle