YRC Public Data Repository - Protein Structure Prediction

Protein:	CE01110
Organism:	Caenorhabditis elegans
Length:	266 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE01110.

Description	E-value	Query Range	Subject Range
gi\|7511250 - gi\|7511250\|pir\|\|S40944 hypothetical protein ZK632.12 - Caenorhabditis elegans	198.0	[0..1]	[266..1]
gi\|123993467, gi... - gi\|124000437\|gb\|ABM87727.1\| pleckstrin homology domain containing, family F (with FYVE domain) membe... PLEKHF2 - pleckstrin homology domain containing, family F (with FYVE domain) member 2 gi\|55631052 - gi\|55631052\|ref\|XP_528194.1\| PREDICTED: similar to phafin 2; PH and FYVE domain-containing protein 2...	194.0	[0..1]	[236..1]
PKHF2_MOUSE - Pleckstrin homology domain-containing family F member 2 OS=Mus musculus GN=Plekhf2 PE=1 SV=1	194.0	[0..1]	[236..1]
gi\|109476116, gi... - gi\|34866158\|ref\|XP_342804.1\| PREDICTED: similar to Phafin 2 [Rattus norvegicus], gi\|171847385\|gb\|AAI...	193.0	[0..1]	[236..1]
gi\|125983332, gi... - gi\|54643746\|gb\|EAL32489.1\| GA13242 [Drosophila pseudoobscura pseudoobscura], gi\|125983332\|ref\|XP_001... gi\|54643746\|gb\|E... - GA13242-PA [Drosophila pseudoobscura], GA13242 [Drosophila pseudoobscura pseudoobscura]	192.0	[0..1]	[262..1]
gi\|62859343 - gi\|62859343\|ref\|NP_001016121.1\| hypothetical protein LOC548875 [Xenopus (Silurana) tropicalis]	192.0	[0..1]	[237..1]
gi\|62901986 - gi\|62901986\|gb\|AAY18944.1\| DKFZp762A0711 [synthetic construct]	191.0	[0..2]	[236..26]
gi\|91087327 - gi\|91087327\|ref\|XP_975593.1\| PREDICTED: similar to FYVE finger containing protein [Tribolium castane...	189.0	[0..1]	[262..1]
PKHF2_CHICK - Pleckstrin homology domain-containing family F member 2 OS=Gallus gallus GN=PLEKHF2 PE=2 SV=1	188.0	[0..1]	[230..1]
gi\|220949950, gi... - gi\|220959106\|gb\|ACL92096.1\| CG14782-PA [synthetic construct], gi\|220949950\|gb\|ACL87518.1\| CG14782-PA... FBpp0308661, CG1... - This gene is referred to in FlyBase by the symbol Dmel\CG14782 (CG14782, FBgn0025381). It is a prote...	186.0	[0..1]	[220..1]

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Predicted Domain #1

Region A:
Residues: [1-58]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVDRLVNSEV NSRRMANVEQ CFGKMGEQLS VFGRVLVGEG VLVKMCRKKP KQRQFFLF

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [59-266]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NDILVYGNIV ISKKRYNKQR ILRLEGVQVE DLEDDGIEKH GWIIKTPAKS FAVYAATETE  60
   61 KREWMLHIER CVTDLLERGN KQAATAHAAV WVPDGEAVKC MVCGKTQFNL VQRRHHCRNC 120
  121 GRVVCGACSS RTFRIDNVHK KPVRVCDHCF DSLSSATPGQ EESEPKTGNR LHHEDSSSDS 180
  181 EDEVNGSGRS SNESRPTFYR EDVQQPAT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	20.39794
Match:	1dvpA
Description:	Hrs
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	1.15122802029718	bayes_pls_golite062009
clathrin binding	0.856903790688531	bayes_pls_golite062009
protein binding	0.31144962654821	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: