YRC Public Data Repository - Protein Structure Prediction

Protein:	CE00922
Organism:	Caenorhabditis elegans
Length:	214 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE00922.

Description	E-value	Query Range	Subject Range
gi\|157775135 - gi\|157775135\|ref\|XP_001665633.1\| hypothetical protein CBG17981 [Caenorhabditis briggsae AF16] gi\|39591551, gi\|... - gi\|39591551\|emb\|CAE71127.1\| Hypothetical protein CBG17981 [Caenorhabditis briggsae], gi\|187025046\|em...	144.0	[0..1]	[211..36]
gi\|91224931, gi\|... - gi\|91224931\|ref\|ZP_01260190.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Vibrio alginol...	131.0	[0..2]	[203..26]
gi\|116185709, gi... - gi\|75856470\|ref\|ZP_00764098.1\| COG2226: Methylase involved in ubiquinone/menaquinone biosynthesis [V...	130.0	[0..2]	[203..26]
gi\|149746384, gi... - gi\|153840045\|ref\|ZP_01992712.1\| ubiquinone/menaquinone biosynthesis methyltransferase UbiE [Vibrio p... UBIE_VIBPA - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Vibrio parahaemolyticus serotype O3:... UBIE_VIBPA - Ubiquinone/menaquinone biosynthesis methyltransferase ubiE OS=Vibrio parahaemolyticus GN=ubiE PE=3 S...	130.0	[0..2]	[203..26]
gi\|84386296, gi\|... - gi\|84386296\|ref\|ZP_00989324.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Vibrio splendi...	130.0	[0..2]	[203..31]
gi\|47013898, gi\|... - gi\|47097727\|ref\|ZP_00235228.1\| 2-heptaprenyl-1,4-naphthoquinone methyltransferase [Listeria monocyto... gi\|126943708, gi... - gi\|254899372\|ref\|ZP_05259296.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Listeria mono... gi\|127765209, gi... - gi\|254912489\|ref\|ZP_05262501.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Listeria mono... gi\|133732157, gi... - gi\|254936816\|ref\|ZP_05268513.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Listeria mono...	129.0	[0..2]	[203..5]
UBIE_LISIN - Demethylmenaquinone methyltransferase OS=Listeria innocua GN=ubiE PE=3 SV=1 UBIE_LISMO - Demethylmenaquinone methyltransferase OS=Listeria monocytogenes GN=ubiE PE=3 SV=1 MENG_LISIN - Demethylmenaquinone methyltransferase OS=Listeria innocua serovar 6a (strain CLIP 11262) GN=menG PE=... gi\|47094454, gi\|... - gi\|47094454\|ref\|ZP_00232134.1\| 2-heptaprenyl-1,4-naphthoquinone methyltransferase [Listeria monocyto... UBIE_LISMC - Menaquinone biosynthesis methyltransferase ubiE OS=Listeria monocytogenes serotype 4b (strain Clip81... gi\|254825574 - gi\|254825574\|ref\|ZP_05230575.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Listeria mono... gi\|254852834 - gi\|254852834\|ref\|ZP_05242182.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Listeria mono... gi\|254877951 - gi\|254877951\|ref\|ZP_05250661.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Listeria mono... MENG_LISMC - Demethylmenaquinone methyltransferase OS=Listeria monocytogenes serotype 4b (strain CLIP80459) GN=me... MENG_LISMF - Demethylmenaquinone methyltransferase OS=Listeria monocytogenes serotype 4b (strain F2365) GN=menG P... gi\|254993470 - gi\|254993470\|ref\|ZP_05275660.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Listeria mono... MENG_LISMO - Demethylmenaquinone methyltransferase OS=Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / ... gi\|255521039 - gi\|255521039\|ref\|ZP_05388276.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Listeria mono... gi\|254831468, gi... - gi\|254831468\|ref\|ZP_05236123.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Listeria mono... gi\|153167788, gi... - gi\|153167788\|ref\|ZP_01927873.1\| 2-heptaprenyl-1,4-naphthoquinone methyltransferase [Listeria monocyt... gi\|254827184, gi... - gi\|254827184\|ref\|ZP_05231871.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Listeria mono... gi\|153202924, gi... - gi\|254931898\|ref\|ZP_05265257.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Listeria mono... gi\|224498619 - gi\|224498619\|ref\|ZP_03666968.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Listeria mono... gi\|224501270 - gi\|224501270\|ref\|ZP_03669577.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Listeria mono...	129.0	[0..2]	[203..5]
gi\|218321183, gi... - gi\|218708164\|ref\|YP_002415785.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Vibrio splen... gi\|85835662, gi\|... - gi\|86146605\|ref\|ZP_01064927.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Vibrio sp. MED...	129.0	[0..2]	[203..31]
gi\|157130331, gi... - gi\|157130331\|ref\|XP_001655665.1\| hypothetical protein AaeL_AAEL011749 [Aedes aegypti], gi\|108871917\|...	129.0	[0..4]	[212..101]
UBIE_VIBCH - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Vibrio cholerae serotype O1 (strain ... UBIE_VIBCM - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Vibrio cholerae serotype O1 (strain ... gi\|229508366, gi... - gi\|229508366\|ref\|ZP_04397870.1\| ubiquinone/menaquinone biosynthesis methyltransferase UbiE/COQ5 [Vib... gi\|229346129, gi... - gi\|229517066\|ref\|ZP_04406512.1\| ubiquinone/menaquinone biosynthesis methyltransferase UbiE/COQ5 [Vib... gi\|229520118, gi... - gi\|229520118\|ref\|ZP_04409546.1\| ubiquinone/menaquinone biosynthesis methyltransferase UbiE/COQ5 [Vib... gi\|229527169, gi... - gi\|229527169\|ref\|ZP_04416563.1\| ubiquinone/menaquinone biosynthesis methyltransferase UbiE/COQ5 [Vib... gi\|229369296, gi... - gi\|229606641\|ref\|YP_002877289.1\| ubiquinone/menaquinone biosynthesis methyltransferase UbiE/COQ5 [Vi... gi\|121587669, gi... - gi\|121587669\|ref\|ZP_01677432.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c... gi\|124115249, gi... - gi\|153214643\|ref\|ZP_01949519.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c... gi\|254851469, gi... - gi\|75829374\|ref\|ZP_00758679.1\| COG2226: Methylase involved in ubiquinone/menaquinone biosynthesis [V... gi\|153222877, gi... - gi\|153222877\|ref\|ZP_01953501.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c... gi\|153801700, gi... - gi\|153801700\|ref\|ZP_01956286.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c... gi\|116216422, gi... - gi\|75823221\|ref\|ZP_00752740.1\| COG2226: Methylase involved in ubiquinone/menaquinone biosynthesis [V... gi\|153818222, gi... - gi\|153818222\|ref\|ZP_01970889.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c... UBIE_VIBC3 - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Vibrio cholerae serotype O1 (strain ... gi\|126520347, gi... - gi\|229508952\|ref\|ZP_04398442.1\| ubiquinone/menaquinone biosynthesis methyltransferase UbiE/COQ5 [Vib... gi\|121727801, gi... - gi\|75816414\|ref\|ZP_00746885.1\| COG2226: Methylase involved in ubiquinone/menaquinone biosynthesis [V... gi\|254291829, gi... - gi\|254291829\|ref\|ZP_04962613.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c... gi\|153829106, gi... - gi\|153829106\|ref\|ZP_01981773.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c... UBIE_VIBCH - Ubiquinone/menaquinone biosynthesis methyltransferase ubiE OS=Vibrio cholerae GN=ubiE PE=3 SV=1 gi\|149739586, gi... - gi\|153826648\|ref\|ZP_01979315.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c...	128.0	[0..2]	[203..27]

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Predicted Domain #1

Region A:
Residues: [1-214]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPDKKTLWML NELEGFEKPK IKLEQYATSS ELAVSMMEMI DETIGFEGKK LIDIGCGCGM  60
   61 LMTTAATMYE LETVLGVDID DEALKICSRN LETAEVQDRC ELLQADILDP ESDLPRGTFD 120
  121 VAVINPPFGT KNNAGIDMQF VQIGLQMVRP GGSVFSLHKS STRDYILKNA KKWDGVGAEC 180
  181 CAEMRWQLPA TYKFHKQKAV DIAVDLIHFK KLDS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	21.221849
Match:	1wy7A
Description:	crystal structure of a putative RNA methyltransferase PH1948 from Pyrococcus horikoshii
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transferase activity	0.444447673749491	bayes_pls_golite062009
catalytic activity	0.352837241386487	bayes_pls_golite062009
methyltransferase activity	0.0533354664784367	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	0.0416815045255102	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: