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View Structure Prediction Details

Protein: mig-10
Organism: Caenorhabditis elegans
Length: 650 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for mig-10.

Description E-value Query
Range
Subject
Range
gi|56207000 - gi|56207000|emb|CAI24283.1| ortholog of human Ras association (RalGDS\/AF-6) and pleckstrin homology...
590.0 [0..10] [505..69]

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Predicted Domain #1
Region A:
Residues: [1-165]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYHDRRRTGF RQYETYMKQK QSADWQLDEL LEELEALETQ LNSSNGGDQL LLGVSGIPAS  60
   61 SSRENVKSIS TLPPPPPALS YHQTPQQPQL LHHHNNHLGY QNGIHQITSI NSAASSCSSP 120
  121 DGDSAFGDSS STESSNNRCR NSAFSSNDSC RDSLNTPSPT QVSPR

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [166-303]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NGELNAEEAK AQKIRQALEK MKEAKVTKIF VKFFVEDGEA LQLLIDERWT VADTLKQLAE  60
   61 KNHIALMEDH CIVEEYPELY IKRVYEDHEK VVENIQMWVQ DSPNKLYFMR RPDKYAFISR 120
  121 PELYLLTPKT SDHMEIPS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 32.69897
Match: 1wgrA
Description: Solution Structure of the RA Domain of Human Grb7 Protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.0934358341245259 bayes_pls_golite062009
protein binding 0.03789551947602 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [304-450]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GDQWTIDVKQ KFVSEYFHRE PVVPPEMEGF LYLKSDGRKS WKKHYFVLRP SGLYYAPKSK  60
   61 KPTTKDLTCL MNLHSNQVYT GIGWEKKYKS PTPWCISIKL TALQMKRSQF IKYICAEDEM 120
  121 TFKKWLVALR IAKNGAELLE NYERACQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.0
Match: 2yryA
Description: No description for 2yryA was found.

Predicted Domain #4
Region A:
Residues: [451-548]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IRRETLGPAS SMSAASSSTA ISEVPHSLSH HQRTPSVASS IQLSSHMMNN PTHPLSVNVR  60
   61 NQSPASFSVN SCQQSHPSRT SAKLEIQYDE QPTGTIKR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [549-650]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 APLDVLRRVS RASTSSPTIP QEESDSDEEF PAPPPVASVM RMPPPVTPPK PCTPLTSKKA  60
   61 PPPPPKRSDT TKLQSASPMA PAKNDLEAAL ARRREKMATM EC

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.69897
Match: 1mw4A
Description: Solution structure of the human Grb7-SH2 domain in complex with a 10 amino acid peptide pY1139
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle