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View Structure Prediction Details

Protein: CE00123
Organism: Caenorhabditis elegans
Length: 398 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE00123.

Description E-value Query
Range
Subject
Range
gi|114108003 - gi|114108003|gb|AAI22960.1| LOC779554 protein [Xenopus tropicalis]
400.0 [0..2] [395..201]

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Predicted Domain #1
Region A:
Residues: [1-320]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDWKITIFTY NLAMKASDSE AVHNMLNGMI DDHTHLVAIG LQEVAHSETI GGAVLTWATT  60
   61 IASWMNTNGR MVLLAKTFQA TNQVLIFGRK QLIGQIKRID YRFQRNTMGG LTGHKGSIGV 120
  121 RLQLASPYSI VFVDSHFIHG PENYGKRVEQ YHTNRNCSFP EDKSVRAAFW FGDFNFRVEE 180
  181 DVNTVIRKIK NGTHLELLDT REQLKRALVE RDAFIGFHEQ PVTFEPTYRV TVGTTEQDGK 240
  241 RVPSWTDRIL YKGDGITGLS YTNNKKAVAS DHLPVVAMFR VTAPAAPKPQ WEVIFEHLPT 300
  301 WYTSIPLVGR FQVNELYYKE 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 75.522879
Match: 1i9yA
Description: Synaptojanin, IPP5C domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
hydrolase activity, acting on ester bonds 1.38680179623768 bayes_pls_golite062009
hydrolase activity 1.35104492673013 bayes_pls_golite062009
catalytic activity 1.22250973382424 bayes_pls_golite062009
binding 0.9581659157795 bayes_pls_golite062009
protein binding 0.684037763280105 bayes_pls_golite062009
phosphoric ester hydrolase activity 0.334789763293071 bayes_pls_golite062009
inositol or phosphatidylinositol phosphatase activity 0.32089180748126 bayes_pls_golite062009
phosphatase activity 0.207117490241507 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [321-398]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NGSYRDWIGV FPSSINDCTT ATNWIYAATC FEQVIEGSKF LACEFNNIPA GNYRLGYFSC  60
   61 HLHCLVGLSK VFQIVEQP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle