YRC Public Data Repository - Protein Structure Prediction

Protein:	SPBC409.08
Organism:	Schizosaccharomyces pombe
Length:	539 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBC409.08.

Description	E-value	Query Range	Subject Range
gi\|70984531, gi\|... - gi\|70984531\|ref\|XP_747772.1\| MFS multidrug transporter [Aspergillus fumigatus Af293], gi\|66845399\|gb... gi\|159122556 - gi\|159122556\|gb\|EDP47677.1\| MFS multidrug transporter, putative [Aspergillus fumigatus A1163]	241.0	[0..8]	[537..66]
gi\|39944294, gi\|... - gi\|39944294\|ref\|XP_361684.1\| hypothetical protein MGG_04158 [Magnaporthe grisea 70-15], gb\|EAA50399....	240.0	[0..2]	[537..28]
gi\|49072098, gi\|... - gi\|71016129\|ref\|XP_758870.1\| hypothetical protein UM02723.1 [Ustilago maydis 521], ref\|XP_400338.1\| ...	237.0	[0..3]	[537..77]
gi\|42554903, gi\|... - gi\|46136363\|ref\|XP_389873.1\| hypothetical protein FG09697.1 [Gibberella zeae PH-1], gi\|42554903\|gb\|E...	235.0	[0..3]	[537..34]
gi\|67668083, gi\|... - gi\|67668083\|ref\|ZP_00465278.1\| General substrate transporter:Major facilitator superfamily [Burkhold...	228.0	[0..39]	[538..982]
gi\|88184223, gi\|... - gi\|88184223\|gb\|EAQ91691.1\| hypothetical protein CHGG_03626 [Chaetomium globosum CBS 148.51], gi\|1162...	226.0	[0..13]	[484..104]
gi\|21214009 - gi\|21214009\|emb\|CAD32176.1\| multidrug resistant protein [Acremonium chrysogenum]	218.0	[0..13]	[537..2]
gi\|169597637, gi... - gi\|169597637\|ref\|XP_001792242.1\| hypothetical protein SNOG_01606 [Phaeosphaeria nodorum SN15], gi\|11...	217.0	[0..5]	[537..121]
gi\|49657230 - gi\|49657230\|emb\|CAG90006.1\| DEHA2G00616p [Debaryomyces hansenii] gi\|50425927, gi\|... - gi\|50425927\|ref\|XP_461560.1\| hypothetical protein DEHA0G00847g [Debaryomyces hansenii CBS767], gi\|49...	216.0	[0..43]	[537..79]
gi\|49650092 - gi\|49650092\|emb\|CAG79818.1\| YALI0E21241p [Yarrowia lipolytica] gi\|49650092, gi\|... - gi\|50553624\|ref\|XP_504223.1\| YALI0E21241p [Yarrowia lipolytica], gi\|49650092\|emb\|CAG79818.1\| unnamed...	215.0	[0..17]	[533..54]

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Predicted Domain #1

Region A:
Residues: [1-539]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPLEKTNTHD STATVEDQEA TDNPMHLTQS RIQSETLFPN GVDLNYPFTT TRGPPDVAEY  60
   61 NLETAEGVYR DPTINEGEEE LVTWELNDPE NPHNWSRLWK WYITIVNSLL VVCSAFGSSV 120
  121 IAGDLEDVSR DLKVGPEVAN LSCSLMVVGF GIGPLVISPL SEMIGRRIVY LVTLMIYIVL 180
  181 QIPCALAPNI ACLLIVRFFC GCFGCTPLTL AGGVISDVWE TRERGLAIAF FAAGPYAGPT 240
  241 LGPLVGGWIG VGTGDFRWIF WVNMIYMFVM YLTLLPVPET YAPVLLRWRA QRIRKETGRQ 300
  301 VFTAQEKQML SFKEIVQVNL TRPLTLLLTE PILVCISGYI ALIYALLYGY FFAYPNVFVK 360
  361 GKGYNEGITG LMFIPILVGV VGALSTTPFL EKQYMAKLDA NNGKSVPEWR LVGMCIASPF 420
  421 IPTGLLIFAW TSFPRLIWIG PAFSGAPFGY GMVLFYFSAN NYLIDVYQNY CASALAAKTM 480
  481 VRSAGGAAFP LFIDYMMDGM TRQWAFFLLG MVAVAAIPIP FTFYLFGDKI RARSKAAIV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	34.045757
Match:	1pw4A
Description:	Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transporter activity	4.09176719149278	bayes_pls_golite062009
substrate-specific transporter activity	3.59744164024479	bayes_pls_golite062009
transmembrane transporter activity	3.5865018981083	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	3.54194478414824	bayes_pls_golite062009
ion transmembrane transporter activity	2.21266150105753	bayes_pls_golite062009
cation transmembrane transporter activity	1.79369588808394	bayes_pls_golite062009
active transmembrane transporter activity	1.59419818573076	bayes_pls_golite062009
organic acid transmembrane transporter activity	1.24937104052238	bayes_pls_golite062009
secondary active transmembrane transporter activity	1.22264637452409	bayes_pls_golite062009
binding	1.01584233411372	bayes_pls_golite062009
alcohol transmembrane transporter activity	0.924836669821548	bayes_pls_golite062009
polyol transmembrane transporter activity	0.924836669821548	bayes_pls_golite062009
glycerol transmembrane transporter activity	0.812001619402678	bayes_pls_golite062009
symporter activity	0.74591237387473	bayes_pls_golite062009
solute:cation symporter activity	0.74591237387473	bayes_pls_golite062009
cation:sugar symporter activity	0.143419068761182	bayes_pls_golite062009
sugar:hydrogen symporter activity	0.143419068761182	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: