YRC Public Data Repository - Protein Structure Prediction

Protein:	SPBC3E7.05c
Organism:	Schizosaccharomyces pombe
Length:	550 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBC3E7.05c.

Description	E-value	Query Range	Subject Range
gi\|70870905 - gi\|70870905\|gb\|EAN85153.1\| hypothetical protein, conserved [Trypanosoma cruzi] gi\|71409302 - gi\|71409302\|ref\|XP_807004.1\| hypothetical protein [Trypanosoma cruzi strain CL Brener]	176.0	[0..9]	[550..529]
gi\|68129234 - gi\|68129234\|emb\|CAJ07774.1\| hypothetical protein, conserved [Leishmania major] gi\|157875544 - gi\|157875544\|ref\|XP_001686160.1\| hypothetical protein [Leishmania major strain Friedlin]	171.0	[0..2]	[550..962]
gi\|68388302 - gi\|68388302\|ref\|XP_696268.1\| PREDICTED: similar to slow myosin heavy chain 1 [Danio rerio]	171.0	[0..12]	[550..2333]
gi\|50757621 - gi\|50757621\|ref\|XP_415581.1\| PREDICTED: similar to fast myosin heavy chain isoform 3 [Gallus gallus]	169.0	[0..12]	[549..1440]

Back

Predicted Domain #1

Region A:
Residues: [1-119]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNRQLRTVKS CFSLQKTHQY RSFWIQSSLR ALPPDVKQNK TEPIPFVPKP EEGSSNKSNS  60
   61 SKFRKRFLLL FLLGITGYSC SVVYCFKDPN FYDYFAEHTP FGKQVLYNVE QSWIGYKYL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	8.0
Match:	2tmaA
Description:	Tropomyosin
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [120-467]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GGNRIKVDDS SPKLKQNSNN ISKKQNSSRN DDTKVKKDTT IERPESLVVE IVDLPSEVTK  60
   61 DTAEESVWKD IGLDQETGLS VTAIPIITET LDHAHEQEIK DQSLRFESSL NEANELHGKL 120
  121 SKIQQEQEHL FEQRLREKVS EMESKLEALL IARDEKWQSA FESEKLRLQK LHEARLQQEL 180
  181 FKLASVFESK LKNELTEQAI TLEKLHLQSI KAQVEQERGS RLGRLQELRN SFQQLQELVR 240
  241 VVLHENGRVT RLVDVSNTLD DLNKDMRFHK LSEVRQHVNT LKEATKDDEL AALASRVIEK 300
  301 IVDSGPILDK EELQTKFDTL SKEIYKTCFL TTESGFFGHL KSIILSQL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	17.30103
Match:	1i84S
Description:	Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [468-550]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PAAVFKSPDI VSVKKTLEDA RSHLLKDDLD GSVRALLSLS QWPRALSRDW INACRRRMEL  60
   61 QQAIEIIKAS ATLSSQLEDA QQA

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.864	0.351	mitochondrion	a.7.3	Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits