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View Structure Prediction Details

Protein: SPBC4F6.05c
Organism: Schizosaccharomyces pombe
Length: 384 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBC4F6.05c.

Description E-value Query
Range
Subject
Range
gi|114673353 - gi|114673353|ref|XP_512155.2| PREDICTED: lectin, mannose-binding, 1 isoform 3 [Pan troglodytes]
294.0 [0..3] [346..17]
gi|631132, gi|433938 - pir||S42626 ER-golgi intermediate compartment protein - human, gi|433938|emb|CAA50653.1| ERGIC53 [Ho...
293.0 [0..3] [346..17]
LMAN1_CHLAE - Protein ERGIC-53 OS=Chlorocebus aethiops GN=LMAN1 PE=2 SV=1
289.0 [0..3] [346..17]
gi|109122312 - gi|109122312|ref|XP_001087928.1| PREDICTED: lectin, mannose-binding, 1 isoform 1 [Macaca mulatta]
289.0 [0..3] [346..17]

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Predicted Domain #1
Region A:
Residues: [1-250]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKFCSLFHVL SFCCTLAYAV PKSQFLQLHS LSNAIPVEWK WYGSVDEDSG YVYLTSKDSN  60
   61 EARSGSLWST SVLRQVGWQL STSFVAHVSE NENTFFAIWY TSAVGSEGPV FGASDKWDGL 120
  121 LISQEIDQTG KIFVRGYLND KSFELAQFTD PDLPPFAKCT IESSPEALNN IILKYGDQSG 180
  181 LELFVNDKPC FQVKDVILPQ GYYFGVSSQS TSAKDLVALS NLNILPPDTS NNENLNPTSN 240
  241 TKQSVGDNTS 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 59.69897
Match: 1r1zA
Description: The Crystal structure of the Carbohydrate recognition domain of the glycoprotein sorting receptor p58/ERGIC-53 reveals a novel metal binding site and conformational changes associated with calcium ion binding
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.52142098960755 bayes_pls_golite062009
transporter activity 1.29150662073327 bayes_pls_golite062009
protein binding 1.15590148654655 bayes_pls_golite062009
transmembrane transporter activity 1.07075219961504 bayes_pls_golite062009
carbohydrate binding 0.706875336696662 bayes_pls_golite062009
substrate-specific transporter activity 0.546512480767482 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.301823428566403 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [251-384]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PQTVIDTEGL NAIKADLAKL FNLVESQRQK MDSLHFALTN ALERLNDISS TSQFPSERFN  60
   61 ALEKLLHDSL SAQSSTADGT SKHLAEFEKE IKKAMGNAYS PYNLTNFMVF LLLGAIVSYG 120
  121 IMLVRRDRRR HKYL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle