YRC Public Data Repository - Protein Structure Prediction

Protein:	SPAC8F11.08c
Organism:	Schizosaccharomyces pombe
Length:	376 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAC8F11.08c.

Description	E-value	Query Range	Subject Range
gi\|7381418, gi\|1... - gi\|7381418\|gb\|AAF61480.1\|AF178685_1 butyrylcholinesterase [Equus caballus], gi\|126352540\|ref\|NP_0010...	230.0	[0..66]	[369..33]
gi\|34810859, gi\|... - gi\|60594005\|pdb\|1XLW\|A Chain A, Diethylphosphorylated Butyrylcholinesterase (Nonaged) Obtained By Re...	229.0	[0..66]	[369..5]
gi\|114590210 - gi\|114590210\|ref\|XP_516857.2\| PREDICTED: butyrylcholinesterase [Pan troglodytes]	229.0	[0..61]	[369..69]
gi\|55730793 - gi\|55730793\|emb\|CAH92116.1\| hypothetical protein [Pongo abelii] gi\|197097436 - gi\|197097436\|ref\|NP_001127509.1\| butyrylcholinesterase [Pongo abelii]	226.0	[0..61]	[369..28]
CHLE_RABIT - Cholinesterase OS=Oryctolagus cuniculus GN=BCHE PE=2 SV=1	226.0	[0..65]	[369..11]
gi\|109508329 - gi\|109508329\|ref\|XP_001056053.1\| PREDICTED: similar to carboxylesterase 5 [Rattus norvegicus]	226.0	[0..50]	[376..17]
gi\|74003707 - gi\|74003707\|ref\|XP_545267.2\| PREDICTED: similar to Cholinesterase precursor (Acylcholine acylhydrola...	226.0	[0..66]	[369..33]
CHLE_FELCA - Cholinesterase OS=Felis catus GN=BCHE PE=2 SV=1	226.0	[0..66]	[370..33]

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Predicted Domain #1

Region A:
Residues: [1-376]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGFATILYSI WVVLSSFVIL SAYQLEVRKF LVKLLSKIVI GASESNVASF FAFVSEKSLE  60
   61 AASVKFVATI IAERMGAQFS SFYDKIFFVD MLGLGSLFAL AAVNVLAARK LESELPASLE 120
  121 PSIGNRDQQK NSSLAKCFSR LFINDLHGTT VKRYPYISYL PNWLLAKNNA ERLVYKSHLL 180
  181 LNAYSPPKSA SASSVIVWVC GAKKSESIII PYLSSLGFFV VVPNYAQPPK FPLSDAVEFV 240
  241 SLCVDWIVEN AIYYDADPER IFFLGEDTGA SVALESLKHI RPNSVKGIFA LCPRSIQNLV 300
  301 WTNQSTIPMM TLHAGDVNPV SDSNDRESSE KASLIKNFVV PGAVPYYYEF TSPRTISTAT 360
  361 FIARWFFLVE DNKKTI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	60.09691
Match:	1p0iA
Description:	Crystal structure of human butyryl cholinesterase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.853693238072967	bayes_pls_golite062009
hydrolase activity	0.729922406043548	bayes_pls_golite062009
binding	0.533666220865844	bayes_pls_golite062009
protein binding	0.177940907664063	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	0.0490144635545247	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: