YRC Public Data Repository - Protein Structure Prediction

Protein:	SPCC1281.04
Organism:	Schizosaccharomyces pombe
Length:	333 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPCC1281.04.

Description	E-value	Query Range	Subject Range
gi\|85775968, gi\|... - gi\|86159457\|ref\|YP_466242.1\| aldo/keto reductase [Anaeromyxobacter dehalogenans 2CP-C], gi\|85775968\|...	330.0	[0..2]	[333..5]
gi\|115365408, gi... - gi\|115377607\|ref\|ZP_01464804.1\| aldo/keto reductase [Stigmatella aurantiaca DW4/3-1], gi\|115365408\|g...	328.0	[0..1]	[332..1]
gi\|53761677, gi\|... - gi\|73543064\|ref\|YP_297584.1\| aldo/keto reductase [Ralstonia eutropha JMP134], gi\|72120477\|gb\|AAZ6274...	326.0	[0..4]	[331..18]
gi\|50119681, gi\|... - gi\|50119681\|ref\|YP_048848.1\| putative aldo/keto reductase [Pectobacterium atrosepticum SCRI1043], gi...	325.0	[0..2]	[332..5]
gi\|68513185, gi\|... - gi\|68560654\|ref\|ZP_00599965.1\| Aldo/keto reductase [Rubrobacter xylanophilus DSM 9941], gi\|68513185\|...	324.0	[0..3]	[332..6]
gi\|66780950, gi\|... - gi\|94986270\|ref\|YP_605634.1\| aldo/keto reductase [Deinococcus geothermalis DSM 11300], gi\|94556551\|g...	323.0	[0..7]	[332..9]
gi\|148265548, gi... - gi\|88934427\|ref\|ZP_01140070.1\| probable oxidoreductase [Geobacter uraniumreducens Rf4], gi\|88918885\|...	322.0	[0..2]	[332..5]
gi\|116050479, gi... - gi\|32037528\|ref\|ZP_00135800.1\| COG0667: Predicted oxidoreductases (related to aryl-alcohol dehydroge...	321.0	[0..4]	[333..8]
gi\|7471099 - pir\|\|E75296 aldo/keto reductase - Deinococcus radiodurans (strain R1) gi\|15807252, gi\|... - gi\|6460065\|gb\|AAF11806.1\|AE002058_6 aldo/keto reductase [Deinococcus radiodurans R1], gi\|15807252\|re...	320.0	[0..6]	[332..11]
gi\|126194344, gi... - gi\|254240966\|ref\|ZP_04934288.1\| hypothetical protein PA2G_01646 [Pseudomonas aeruginosa 2192], gi\|19... gi\|11351605 - pir\|\|H83328 probable oxidoreductase PA2535 [imported] - Pseudomonas aeruginosa (strain PAO1) gi\|218771712, gi... - gi\|218891486\|ref\|YP_002440353.1\| putative oxidoreductase [Pseudomonas aeruginosa LESB58], gi\|2187717... gi\|15597731, gi\|... - gi\|9948592\|gb\|AAG05923.1\|AE004681_5 probable oxidoreductase [Pseudomonas aeruginosa PAO1], gi\|155977...	320.0	[0..4]	[333..8]

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Predicted Domain #1

Region A:
Residues: [1-333]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPIVNGFKVG PIGLGLMGLT WRPKQTPIKQ AFELMNYALS QGSNYWNAGE FYGINPPTAN  60
   61 LDLLADYFEK YPKNADKVFL SVKGGTDFKT LAPHGDPESV TKSVKNALTR LRGKKKLDLF 120
  121 QCARVDHKVP IETTMKALKA FVDSGEISCV GLSEASAESI KRALAIVPIA AVETEYSLFS 180
  181 RDIEKNGILD TCTQLSIPII AYAPFCHGLL TGRVKTAEDL KDFIKAFPFL RNMDKFNPKV 240
  241 FEKNIPFLKA VEQLAQKFGM SMPEFALNFI IANGKGMIIP IPGSTTVQRA ESNLSALKKS 300
  301 LSSEQLEEAK KVLDKHQIFG LRYNKQLEST LSI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	72.045757
Match:	1pyfA
Description:	Structure of NADPH-dependent family 11 aldo-keto reductase AKR11A(apo)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
pyridoxine 4-dehydrogenase activity	3.25535446462297	bayes_pls_golite062009
catalytic activity	1.68179794468736	bayes_pls_golite062009
aldo-keto reductase activity	0.756121063182699	bayes_pls_golite062009
oxidoreductase activity	0.409822872480823	bayes_pls_golite062009
binding	0.1545122191439	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	0.0465377885825481	bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors	0.0143508436041874	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: