YRC Public Data Repository - Protein Structure Prediction

Protein:	dus2
Organism:	Schizosaccharomyces pombe
Length:	479 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for dus2.

Description	E-value	Query Range	Subject Range
gi\|56552023, gi\|... - gi\|56552023\|ref\|YP_162862.1\| tRNA-dihydrouridine synthase [Zymomonas mobilis subsp. mobilis ZM4], gi...	249.0	[0..1]	[355..18]
gi\|110647985, gi... - gi\|110834874\|ref\|YP_693733.1\| NifR3 family TIM-barrel protein [Alcanivorax borkumensis SK2], gi\|1106...	249.0	[0..1]	[340..3]
gi\|5834292 - gi\|5834292\|gb\|AAD53896.1\|AF176314_6 NifR3-like protein [Zymomonas mobilis] gi\|5834292\|gb\|AA... - NifR3-like protein [Zymomonas mobilis]	244.0	[0..1]	[331..18]
gi\|52424587, gi\|... - gi\|52424587\|ref\|YP_087724.1\| hypothetical protein MS0532 [Mannheimia succiniciproducens MBEL55E], gi...	244.0	[0..1]	[340..21]
gi\|126197628, gi... - gi\|84323487\|ref\|ZP_00971556.1\| COG0042: tRNA-dihydrouridine synthase [Pseudomonas aeruginosa 2192], ... DUSB_PSEAE - tRNA-dihydrouridine synthase B OS=Pseudomonas aeruginosa GN=dusB PE=3 SV=1 DUSB_PSEAE - tRNA-dihydrouridine synthase B OS=Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / ... gi\|218893946, gi... - gi\|218893946\|ref\|YP_002442815.1\| putative tRNA-dihydrouridine synthase [Pseudomonas aeruginosa LESB5... gi\|107103951 - gi\|107103951\|ref\|ZP_01367869.1\| hypothetical protein PaerPA_01005022 [Pseudomonas aeruginosa PACS2] gi\|84317460, gi\|... - gi\|84317460\|ref\|ZP_00965903.1\| COG0042: tRNA-dihydrouridine synthase [Pseudomonas aeruginosa C3719],...	241.0	[0..1]	[338..6]
gi\|115588221, gi... - gi\|53726463\|ref\|ZP_00141308.2\| COG0042: tRNA-dihydrouridine synthase [Pseudomonas aeruginosa UCBPP-P...	241.0	[0..1]	[338..6]
gi\|94417464, gi\|... - gi\|94417464\|ref\|ZP_01297282.1\| hypothetical protein PaerP_01000781 [Pseudomonas aeruginosa PA7], gi\|...	240.0	[0..1]	[338..6]
gi\|12721426, gi\|... - gi\|15602952\|ref\|NP_246024.1\| hypothetical protein PM1087 [Pasteurella multocida subsp. multocida str...	240.0	[0..1]	[341..5]
DUSB_PASMU - tRNA-dihydrouridine synthase B OS=Pasteurella multocida GN=dusB PE=3 SV=2 DUSB_PASMU - tRNA-dihydrouridine synthase B OS=Pasteurella multocida (strain Pm70) GN=dusB PE=3 SV=2	240.0	[0..1]	[341..3]
gi\|77996441, gi\|... - gi\|78044326\|ref\|YP_361166.1\| nifR3 family TIM-barrel protein [Carboxydothermus hydrogenoformans Z-29...	240.0	[0..4]	[335..8]

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Predicted Domain #1

Region A:
Residues: [1-345]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGLLNYSNKV CLAPMVRIGE LPMRLLALRY GANLVWGPEI VDKALLSGTP VERVVNDRIN  60
   61 CIDFVKPPSN KVLFRVHPLE ANRLIFQLGS ASPELAVEAA KLVANDVAGI DLNCGCPKHF 120
  121 SVHAGMGAGL LKNQDRLVSI LDALVNEIGK PYKISISCKI RLLETKEDTL KLVERICDTG 180
  181 VRAITVHCRT TPMRNTEPAD RSYLSEIVGV CRNKDVSILV NGDVLSYNDG LDVIEKYGVD 240
  241 GVLIARAAER NVSCFRIEGP LSSFKVAEEF LKMALEVDNN FGNTKYCLNQ IMQGSFRKNV 300
  301 RQLAQTAKTY EDLKKAFEIE YKHSDASSVC PTLEKEKSLV ISFVD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	49.0
Match:	1vhnA
Description:	Crystal structure of a putative flavin oxidoreductase with flavin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.94749091175302	bayes_pls_golite062009
tRNA dihydrouridine synthase activity	1.94490879164338	bayes_pls_golite062009
nucleic acid binding	1.03692680161964	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-CH group of donors	0.876786102965635	bayes_pls_golite062009
oxidoreductase activity	0.80115790656025	bayes_pls_golite062009
binding	0.68572942532795	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [346-479]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPSFLESLLA SNILKQLSRL HFTKIFAVSE EEDICKQLDD IHEKFLCHGI ALSLISADNL  60
   61 ASAIASAHLV ICMEKDESIM NEAVCDQKIT IRLPINSNTN EAVVECENKS MQSKHALDII 120
  121 QERIKDLEEK AQVV

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: