YRC Public Data Repository - Protein Structure Prediction

Protein:	SPAP8A3.07c
Organism:	Schizosaccharomyces pombe
Length:	372 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAP8A3.07c.

Description	E-value	Query Range	Subject Range
gi\|11527262 - gi\|11527262\|gb\|AAG36950.1\|AF283009_1 phe-inhibited DAHP synthase [Aspergillus nidulans]	492.0	[0..1]	[367..1]
gi\|49084614, gi\|... - gi\|67516145\|ref\|XP_657958.1\| hypothetical protein AN0354.2 [Aspergillus nidulans FGSC A4], ref\|XP_40...	490.0	[0..1]	[367..7]
gi\|114193629, gi... - gi\|115396842\|ref\|XP_001214060.1\| phospho-2-dehydro-3-deoxyheptonate aldolase [Aspergillus terreus NI...	487.0	[0..3]	[372..2]
gi\|37678885, gi\|... - gi\|37678885\|ref\|NP_933494.1\| phospho-2-dehydro-3-deoxyheptonate aldolase [Vibrio vulnificus YJ016], ...	487.0	[0..11]	[362..58]
gi\|169766848 - gi\|169766848\|ref\|XP_001817895.1\| hypothetical protein [Aspergillus oryzae RIB40] gi\|83765750 - gi\|83765750\|dbj\|BAE55893.1\| unnamed protein product [Aspergillus oryzae]	486.0	[0..2]	[372..6]
gi\|62126962, gi\|... - gi\|62179329\|ref\|YP_215746.1\| 3-deoxy-7-phosphoheptulonate synthase [Salmonella enterica subsp. enter...	486.0	[0..7]	[366..39]
gi\|73854749, gi\|... - gi\|74311272\|ref\|YP_309691.1\| phospho-2-dehydro-3-deoxyheptonate aldolase [Shigella sonnei Ss046], gi...	483.0	[0..18]	[366..6]
gi\|42545648, gi\|... - gi\|46107190\|ref\|XP_380654.1\| hypothetical protein FG00478.1 [Gibberella zeae PH-1], gi\|42545648\|gb\|E...	483.0	[0..2]	[372..3]
gi\|66847593, gi\|... - gi\|70990224\|ref\|XP_749961.1\| phospho-2-dehydro-3-deoxyheptonate aldolase [Aspergillus fumigatus Af29...	483.0	[0..4]	[372..61]
gi\|193069560, gi... - gi\|75235771\|ref\|ZP_00719926.1\| COG0722: 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase ...	483.0	[0..18]	[366..6]

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Predicted Domain #1

Region A:
Residues: [1-372]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSPVFLPSGE TYDQEHLDDN RVLGYNPLVP AALVQQEIPV SETSRKVITD SRKEIQAILN  60
   61 KQDDRIIVVV GPCSIHDPKL AMDYAKLLKP KADELQDALC VVMRCYLEKP RTTIGWKGLV 120
  121 NDPNLDGSFA INKGIRMARQ MYCDVTNFGI PLASEMLDNI SPQFFADLLS FGAIGARTTE 180
  181 SQLHRELASA LSFPVGFKNG TDGTVGVAID AIGATAHPHT MLGVTKQGLA AITMTRGNKD 240
  241 TFIILRGGKK GPNYDAEHVA AVRKDLEKAN LPPRIMIDCS HGNSSKNHLN QPKVSKSIAE 300
  301 QIRNGDSSIV GVMIESHINE GRQDAPIRPG VKDTLKYGVS ITDACVSWEQ TAPMLDDLAE 360
  361 AVRARRQNQK SN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	131.0
Match:	1hfbA
Description:	3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (DAHP synthase, AroG)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
3-deoxy-7-phosphoheptulonate synthase activity	2.72022882819661	bayes_pls_golite062009
catalytic activity	2.67031204377352	bayes_pls_golite062009
lyase activity	0.740424046054758	bayes_pls_golite062009
transferase activity, transferring aldehyde or ketonic groups	0.719960432098845	bayes_pls_golite062009
oxo-acid-lyase activity	0.606352769346285	bayes_pls_golite062009
ligase activity, forming carbon-carbon bonds	0.490222900376021	bayes_pls_golite062009
transferase activity	0.464721888799972	bayes_pls_golite062009
carbon-carbon lyase activity	0.36754360512349	bayes_pls_golite062009
3-deoxy-8-phosphooctulonate synthase activity	0.0356008407895519	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: