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View Structure Prediction Details

Protein: SPBC25H2.16c
Organism: Schizosaccharomyces pombe
Length: 533 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBC25H2.16c.

Description E-value Query
Range
Subject
Range
AP1G1_MOUSE - AP-1 complex subunit gamma-1 OS=Mus musculus GN=Ap1g1 PE=1 SV=3
gi|227469 - gi|227469|prf||1704251A gamma adaptin
368.0 [0..3] [529..263]
gi|189491695, gi... - gi|189491695|ref|NP_604455.1| adaptor-related protein complex 1, gamma 1 subunit [Rattus norvegicus]...
367.0 [0..3] [529..263]
gi|190690387, gi... - gi|190691767|gb|ACE87658.1| adaptor-related protein complex 1, gamma 1 subunit protein [synthetic co...
gi|23273630 - gi|23273630|gb|AAH36283.1| Adaptor-related protein complex 1, gamma 1 subunit [Homo sapiens]
367.0 [0..3] [529..266]
gi|73957078, gi|... - gi|73957078|ref|XP_862646.1| PREDICTED: similar to Adapter-related protein complex 1 gamma 1 subunit...
366.0 [0..3] [529..263]

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Predicted Domain #1
Region A:
Residues: [1-350]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSAKRRLYS LIQNATEPYA FEPDLAVNLD IADLINQTGG NLPREAAFAI VRKVNDRNPT  60
   61 VAYLALNLLD ICVKNCGYAF RLQIASKEFL NELVRRFPER PPSRLNKIQV MILSLIEEWR 120
  121 KTICRVDRYK EDLGFIRDMH RLLSYKGYTF PEIDKENLAV LSQKSVLKTA EELEKEDREA 180
  181 MSAKLQELIR RGTPADLAEA NKLMKVMAGY DTEQKQKYKE HVLVDLEKVK RKAALFGEML 240
  241 NEVSESDKLA SGDLYDELAY SLKAAQRKVD KILEEMSPED DSYVTVSDLK SLIASLLTQY 300
  301 DHLLEGDFSS ARTVAADNNS LLQATTESAK SNSKTSANAS NTQSAMDLLI 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 50.30103
Match: 1w63A
Description: AP1 clathrin adaptor core
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [351-533]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DLDIGSDAQS PSLPASSSQM PTSSFNMESL SQSLLGTVEA PAEVGAISLT ESFNSPVSNS  60
   61 SPNVPINNFT STCAFENSHL NFQITPKSKT RDQVVLLATY TNLSPYDTVE NLQSFIAVPK 120
  121 KYNLVLQPQS GTNLSPLQKD GIYQEMIVTK LLDVTELPVR FKLTYKVNGR SQEYTGQSSI 180
  181 RLL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 31.0
Match: 1iu1A
Description: Gamma1-adaptin domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein binding 1.57801165255065 bayes_pls_golite062009
binding 1.4853299341494 bayes_pls_golite062009
transporter activity 0.169557557237959 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle