YRC Public Data Repository - Protein Structure Prediction

Protein:	sib2
Organism:	Schizosaccharomyces pombe
Length:	431 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for sib2.

Description	E-value	Query Range	Subject Range
gi\|17129737, gi\|... - gi\|17227888\|ref\|NP_484436.1\| hypothetical protein all0392 [Nostoc sp. PCC 7120], gi\|17129737\|dbj\|BAB... gi\|25300706 - pir\|\|AG1855 hypothetical protein all0392 [imported] - Nostoc sp. (strain PCC 7120)	181.0	[0..5]	[430..6]
gi\|46135373, gi\|... - gi\|75909047\|ref\|YP_323343.1\| monooxygenase [Anabaena variabilis ATCC 29413], gi\|75702772\|gb\|ABA22448...	174.0	[0..5]	[430..6]
gi\|77458086, gi\|... - gi\|77458086\|ref\|YP_347591.1\| L-ornithine N5-oxygenase [Pseudomonas fluorescens Pf0-1], gi\|77382089\|g...	173.0	[0..1]	[429..1]
gi\|91686953, gi\|... - gi\|91782999\|ref\|YP_558205.1\| dihydrolipoamide dehydrogenase [Burkholderia xenovorans LB400], gi\|9168...	171.0	[0..1]	[425..1]
gi\|11037217 - gi\|11037217\|gb\|AAG27518.1\|AF230494_1 L-ornithine N5-hydroxylase [Pseudomonas sp. B10]	171.0	[0..1]	[428..1]
gi\|110648061, gi... - gi\|110834950\|ref\|YP_693809.1\| L-ornithine N5-oxygenase [Alcanivorax borkumensis SK2], gi\|110648061\|e...	170.0	[0..2]	[425..5]
gi\|23097835, gi\|... - gi\|23097835\|ref\|NP_691301.1\| monooxygenase [Oceanobacillus iheyensis HTE831], gi\|22776059\|dbj\|BAC123...	170.0	[0..1]	[430..1]
gi\|83617067 - gi\|83617067\|ref\|ZP_00927608.1\| COG3486: Lysine/ornithine N-monooxygenase [Burkholderia mallei FMH] gi\|83622917 - gi\|83622917\|ref\|ZP_00933207.1\| COG3486: Lysine/ornithine N-monooxygenase [Burkholderia mallei JHU] gi\|67638639, gi\|... - gi\|67638639\|ref\|ZP_00437574.1\| COG3486: Lysine/ornithine N-monooxygenase [Burkholderia mallei 10399]... gi\|67639167 - gi\|67639167\|ref\|ZP_00438059.1\| COG3486: Lysine/ornithine N-monooxygenase [Burkholderia mallei GB8 ho... gi\|53723402, gi\|... - gi\|53723402\|ref\|YP_102861.1\| l-ornithine 5-monooxygenase [Burkholderia mallei ATCC 23344], gi\|524268...	170.0	[0..5]	[416..7]
gi\|78066259, gi\|... - gi\|78066259\|ref\|YP_369028.1\| lysine/ornithine N-monooxygenase [Burkholderia sp. 383], gi\|77967004\|gb...	169.0	[0..5]	[428..7]
gi\|167894312 - gi\|167894312\|ref\|ZP_02481714.1\| putative L-ornithine 5-monooxygenase [Burkholderia pseudomallei 7894... gi\|167815830 - gi\|167815830\|ref\|ZP_02447510.1\| putative L-ornithine 5-monooxygenase [Burkholderia pseudomallei 91] gi\|52209804, gi\|... - gi\|53719390\|ref\|YP_108376.1\| putative L-ornithine 5-monooxygenase [Burkholderia pseudomallei K96243]...	169.0	[0..5]	[416..7]

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Predicted Domain #1

Region A:
Residues: [1-431]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTEPLDLAII GFGPASLSFL IALHDHSEEP LKNKKIRVFE KLPTFSWHEG MLIPGSNMQI  60
   61 SFVKDLATPR DPTSYFTFLN YLHSHGQERL SGFLNMSTLE PSRYEYHDYL CWAASHFSKF 120
  121 VEYNANINKL HYDAATDLYI VGHGDTQWQA KNIIITTGCQ PYIPPLYKSV DSPLIVHSSK 180
  181 FMSDHSQKLL RNSKHGILVV GCGQSAAEIW KHCHYSLDPK TPLAMCFRNL APVPSDSSPF 240
  241 VNSLYFDSHN SHWWYNLPTE ARLKGLSVGR TTNYSVVKES LLEEMFKECY LQKLRYGQEF 300
  301 HQIMGDTDIQ SIKNEGDHLV VQLTSQMDKS KKPETRKIDV LYVATGYDHE SFDVLMSSLF 360
  361 PNSQGAQISE EYCVLNAPSK QGKVYVAGIT SNQHGIGETL LSWAAIRAGG LAKELFGPSK 420
  421 PTARVPASYL N

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	39.221849
Match:	1ebdA
Description:	Dihydrolipoamide dehydrogenase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.56773888754354	bayes_pls_golite062009
binding	1.2242882154922	bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors	1.2200832751675	bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor	1.20561532241252	bayes_pls_golite062009
antioxidant activity	0.534236777994249	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH	0.447633601939918	bayes_pls_golite062009
NADPH-adrenodoxin reductase activity	0.364308821777151	bayes_pls_golite062009
thioredoxin-disulfide reductase activity	0.360698026159114	bayes_pls_golite062009
protein binding	0.0171008177759692	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: