YRC Public Data Repository - Protein Structure Prediction

Protein:	apl1
Organism:	Schizosaccharomyces pombe
Length:	677 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for apl1.

Description	E-value	Query Range	Subject Range
gi\|114668034 - gi\|114668034\|ref\|XP_001174142.1\| PREDICTED: adaptor-related protein complex 2, beta 1 subunit isofor...	457.0	[0..3]	[623..2]
AP2B1 - adaptor-related protein complex 2, beta 1 subunit gi\|149724034 - gi\|149724034\|ref\|XP_001503976.1\| PREDICTED: similar to beta-chain clathrin associated protein comple... AP2B1_RAT - AP-2 complex subunit beta OS=Rattus norvegicus GN=Ap2b1 PE=1 SV=1 gi\|73966773 - gi\|73966773\|ref\|XP_867698.1\| PREDICTED: similar to Adapter-related protein complex 2 beta 1 subunit ... gi\|114668040, gi... - gi\|114668042\|ref\|XP_001174162.1\| PREDICTED: adaptor-related protein complex 2, beta 1 subunit isofor... gi\|168277614 - gi\|168277614\|dbj\|BAG10785.1\| AP-2 complex subunit beta-1 [synthetic construct]	455.0	[0..3]	[623..2]
AP2B1_MOUSE - AP-2 complex subunit beta OS=Mus musculus GN=Ap2b1 PE=1 SV=1	454.0	[0..3]	[623..2]
gi\|114668030, gi... - gi\|114668032\|ref\|XP_001174152.1\| PREDICTED: similar to beta-chain clathrin associated protein comple... gi\|149053660, gi... - gi\|73695330\|gb\|AAI03482.1\| Ap2b1 protein [Rattus norvegicus], gi\|203115\|gb\|AAA40808.1\| beta-chain cl... gi\|73966805 - gi\|73966805\|ref\|XP_853723.1\| PREDICTED: similar to adaptor-related protein complex 2, beta 1 subunit... ENSCJAT00000029066 - null gi\|119600547, gi... - gi\|71773106\|ref\|NP_001025177.1\| adaptor-related protein complex 2, beta 1 subunit isoform a [Homo sa... gi\|123993213, gi... - gi\|124000207\|gb\|ABM87612.1\| adaptor-related protein complex 2, beta 1 subunit [synthetic construct],... gi\|149724032 - gi\|149724032\|ref\|XP_001503974.1\| PREDICTED: similar to beta-chain clathrin associated protein comple... CCDS32621.1_1 - null	454.0	[0..3]	[623..2]
AP1B1_BOVIN - AP-1 complex subunit beta-1 OS=Bos taurus GN=AP2B1 PE=2 SV=1	454.0	[0..3]	[623..2]
gi\|73966785 - gi\|73966785\|ref\|XP_867757.1\| PREDICTED: similar to Adapter-related protein complex 2 beta 1 subunit ...	453.0	[0..3]	[623..2]

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Predicted Domain #1

Region A:
Residues: [1-586]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSSSSHFSS TAADLLAVFS SDNKDKSANK RISALKKAIA GISYGYDMSS LFPSVISSME  60
   61 SNNLELKKLC YLYLKIYASV KPTEAKRAVK LILNDIYSSN PMIRSLALRT LTSVNIKNFW 120
  121 VAAMDPIVRL LDDTDPYVRK TAAIGIAKLY SYDKKMVESS GLIDHLKEML SDESSVVVAN 180
  181 SLAALMNIVN SSTGFKLTFS REISNKLVKS LTDCSEWLQV AILDALIFYV PQKPGEAESF 240
  241 AERISPWLQH GNAAVCMGAV KVILYLTNYM KDDNRVKEYF MKTQPPLVTL LARKSSATQY 300
  301 VILRNIQIIL EQCPEMFAND IHFFYCNFDD PIYVKLEKLD ILTKIADIHN LDQILPEFVE 360
  361 YASEIDVELV RKSVKCIGYL AIKIEERKND CIDSLIELMN TKVTYVIQEA VIVIRDILRK 420
  421 YPGSYKSLVP ILYENLDSLD EPDAKSAVIW ILGQYAEEIE DSITLLNDYL KGFFDEPLEI 480
  481 QLTLLTAVIK VFLKKPTAAA DMVTNVLQWC TDEVNDPDLR DRGIIYSRML SANPELAKKV 540
  541 ILANMPPVNV GTGMYDPDTT EQLMLNISTL SSIYHKPPNR FVKGAQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	108.0
Match:	1w63B
Description:	AP1 clathrin adaptor core
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [587-677]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VAYCEPSPVL RLRTRDSNPS NTDSRESNHK KYNHFHQKSQ TRRVMEQYDR NSWNPSPFSD  60
   61 ESNSNTFSGK FDSADQENLG MPMTPETHLM D

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits