YRC Public Data Repository - Protein Structure Prediction

Protein:	SPBC36.01c
Organism:	Schizosaccharomyces pombe
Length:	580 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBC36.01c.

Description	E-value	Query Range	Subject Range
gi\|49072098, gi\|... - gi\|71016129\|ref\|XP_758870.1\| hypothetical protein UM02723.1 [Ustilago maydis 521], ref\|XP_400338.1\| ...	259.0	[0..10]	[578..44]
gi\|39944294, gi\|... - gi\|39944294\|ref\|XP_361684.1\| hypothetical protein MGG_04158 [Magnaporthe grisea 70-15], gb\|EAA50399....	257.0	[0..1]	[577..1]
gi\|42554903, gi\|... - gi\|46136363\|ref\|XP_389873.1\| hypothetical protein FG09697.1 [Gibberella zeae PH-1], gi\|42554903\|gb\|E...	251.0	[0..13]	[577..3]
gi\|70984531, gi\|... - gi\|70984531\|ref\|XP_747772.1\| MFS multidrug transporter [Aspergillus fumigatus Af293], gi\|66845399\|gb... gi\|159122556 - gi\|159122556\|gb\|EDP47677.1\| MFS multidrug transporter, putative [Aspergillus fumigatus A1163]	250.0	[0..17]	[578..45]
gi\|169597637, gi... - gi\|169597637\|ref\|XP_001792242.1\| hypothetical protein SNOG_01606 [Phaeosphaeria nodorum SN15], gi\|11...	244.0	[0..9]	[578..98]
gi\|49650092 - gi\|49650092\|emb\|CAG79818.1\| YALI0E21241p [Yarrowia lipolytica] gi\|49650092, gi\|... - gi\|50553624\|ref\|XP_504223.1\| YALI0E21241p [Yarrowia lipolytica], gi\|49650092\|emb\|CAG79818.1\| unnamed...	234.0	[0..20]	[573..24]
gi\|28924997, gi\|... - gi\|32413306\|ref\|XP_327133.1\| hypothetical protein [Neurospora crassa], gi\|28924997\|gb\|EAA34085.1\| hy... gi\|85110219 - gi\|85110219\|ref\|XP_963321.1\| hypothetical protein NCU06847 [Neurospora crassa OR74A]	229.0	[0..2]	[580..25]
gi\|88184223, gi\|... - gi\|88184223\|gb\|EAQ91691.1\| hypothetical protein CHGG_03626 [Chaetomium globosum CBS 148.51], gi\|1162...	228.0	[0..1]	[524..28]

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Predicted Domain #1

Region A:
Residues: [1-114]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSESSVNADT PKNTNDVLNG AYQSATTEPE GQYRSATDNP SLYQVPTHGS LYRNLSNSAS  60
   61 AYYPANGNMN SREPANELSD ISSLAEKGEL EPPMAKLLSD PDFQGKQFPT VEAP

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [115-580]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ELFIFELAPD SPSIALNWTF WRKMKTTSIY AYASLTIAWG SSVLSPASAT LAKKYHIGMT  60
   61 TSLLNVSLFM LGYCLGPICW APMSEITGRK TPLYIGLFLF SVFQIAVATA QDIQTIMICR 120
  121 FFGGYGACVP LCVVAAAFAD MYPNRYRGTA ITIFAAVIFV GPLVAPIVGG FLTKSYLGWR 180
  181 WTEYITSFMG FLSIILIYLF CEETYLKTIT ENKVQEYREI TGNQLVHARS EEESLSARDI 240
  241 IMNYLLIPLK MLATEPIVFL VSLYCSFVYA IIYLLLEAYP VIFQEGRHFP LGVSALPYIG 300
  301 ILVGVFIGCG INCLFEPWYF RQVIKAGNKP APEARLPPMM IGSFLFPAGI FWLAWSGYYT 360
  361 YVHWIVPTLS GLLTGAGILL IFLQCLNYLL DAYLFRAASV FAANVIMRSA VAGGFPLFAV 420
  421 QMFHNMGVGW AGSLLGFIAT ALIPMPFAFF FFGKKIRAKS KMTAQF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	37.154902
Match:	1pw4A
Description:	Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transporter activity	4.09176719149278	bayes_pls_golite062009
substrate-specific transporter activity	3.59744164024479	bayes_pls_golite062009
transmembrane transporter activity	3.5865018981083	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	3.54194478414824	bayes_pls_golite062009
hexose phosphate transmembrane transporter activity	3.18173622457291	bayes_pls_golite062009
glucose-6-phosphate transmembrane transporter activity	3.18173622457291	bayes_pls_golite062009
sugar:hydrogen symporter activity	2.99050613058546	bayes_pls_golite062009
cation:sugar symporter activity	2.99050613058546	bayes_pls_golite062009
monosaccharide transmembrane transporter activity	2.63293544825311	bayes_pls_golite062009
carbohydrate transmembrane transporter activity	2.62141276633776	bayes_pls_golite062009
sugar transmembrane transporter activity	2.47557586092261	bayes_pls_golite062009
ion transmembrane transporter activity	2.21266150105753	bayes_pls_golite062009
solute:hydrogen symporter activity	2.10485633822652	bayes_pls_golite062009
cation transmembrane transporter activity	1.79369588808394	bayes_pls_golite062009
active transmembrane transporter activity	1.59419818573076	bayes_pls_golite062009
organic acid transmembrane transporter activity	1.24937104052238	bayes_pls_golite062009
secondary active transmembrane transporter activity	1.22264637452409	bayes_pls_golite062009
binding	1.01584233411372	bayes_pls_golite062009
alcohol transmembrane transporter activity	0.924836669821548	bayes_pls_golite062009
polyol transmembrane transporter activity	0.924836669821548	bayes_pls_golite062009
glycerol transmembrane transporter activity	0.812001619402678	bayes_pls_golite062009
solute:cation symporter activity	0.74591237387473	bayes_pls_golite062009
symporter activity	0.74591237387473	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: