YRC Public Data Repository - Protein Structure Prediction

Protein:	SPCC777.15
Organism:	Schizosaccharomyces pombe
Length:	326 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPCC777.15.

Description	E-value	Query Range	Subject Range
gi\|186466566, gi... - gi\|23130352\|ref\|ZP_00112169.1\| COG0042: tRNA-dihydrouridine synthase [Nostoc punctiforme PCC 73102],...	244.0	[0..1]	[325..8]
gi\|5834292 - gi\|5834292\|gb\|AAD53896.1\|AF176314_6 NifR3-like protein [Zymomonas mobilis] gi\|5834292\|gb\|AA... - NifR3-like protein [Zymomonas mobilis]	241.0	[0..2]	[290..9]
gi\|25332175 - pir\|\|AH1959 hypothetical protein all1227 [imported] - Nostoc sp. (strain PCC 7120) gi\|17130574, gi\|... - gi\|17228722\|ref\|NP_485270.1\| hypothetical protein all1227 [Nostoc sp. PCC 7120], gi\|17130574\|dbj\|BAB...	241.0	[0..1]	[325..8]
gi\|67916662, gi\|... - gi\|67916662\|ref\|ZP_00510363.1\| Dihydrouridine synthase TIM-barrel protein nifR3 [Clostridium thermoc... gi\|196253182, gi... - gi\|196253182\|ref\|ZP_03151820.1\| TIM-barrel protein, nifR3 family [Clostridium thermocellum DSM 4150]...	241.0	[0..9]	[324..1]
gi\|56552023, gi\|... - gi\|56552023\|ref\|YP_162862.1\| tRNA-dihydrouridine synthase [Zymomonas mobilis subsp. mobilis ZM4], gi...	239.0	[0..2]	[290..9]
gi\|75906868, gi\|... - gi\|75906868\|ref\|YP_321164.1\| dihydrouridine synthase TIM-barrel protein nifR3 [Anabaena variabilis A...	238.0	[0..1]	[325..8]
gi\|197750239, gi... - gi\|254360638\|ref\|ZP_04976787.1\| tRNA-dihydrouridine synthase [Mannheimia haemolytica PHL213], gi\|197... gi\|110735319 - gi\|110735319\|gb\|ABG89230.1\| putative nitrogen fixation protein [Mannheimia haemolytica]	237.0	[0..9]	[290..1]
gi\|255652101 - gi\|255652101\|ref\|ZP_05399003.1\| tRNA-dihydrouridine synthase [Clostridium difficile QCD-37x79] gi\|145952352, gi... - gi\|90572713\|ref\|ZP_01229237.1\| hypothetical protein CdifQ_02003914 [Clostridium difficile QCD-32g58]... gi\|255102766 - gi\|255102766\|ref\|ZP_05331743.1\| tRNA-dihydrouridine synthase [Clostridium difficile QCD-63q42] gi\|255308587 - gi\|255308587\|ref\|ZP_05352758.1\| tRNA-dihydrouridine synthase [Clostridium difficile ATCC 43255] gi\|255316261 - gi\|255316261\|ref\|ZP_05357844.1\| tRNA-dihydrouridine synthase [Clostridium difficile QCD-76w55] gi\|255518922 - gi\|255518922\|ref\|ZP_05386598.1\| tRNA-dihydrouridine synthase [Clostridium difficile QCD-97b34] gi\|254977180 - gi\|254977180\|ref\|ZP_05273652.1\| tRNA-dihydrouridine synthase [Clostridium difficile QCD-66c26] gi\|255094510 - gi\|255094510\|ref\|ZP_05323988.1\| tRNA-dihydrouridine synthase [Clostridium difficile CIP 107932] gi\|115252617, gi... - gi\|126701180\|ref\|YP_001090077.1\| tRNA-dihydrouridine synthase [Clostridium difficile 630], gi\|115252...	235.0	[0..9]	[313..1]
gi\|67853187, gi\|... - gi\|67924974\|ref\|ZP_00518361.1\| Dihydrouridine synthase TIM-barrel protein nifR3 [Crocosphaera watson...	235.0	[0..1]	[316..8]
gi\|170717873, gi... - gi\|46156521\|ref\|ZP_00204726.1\| COG0042: tRNA-dihydrouridine synthase [Haemophilus somnus 2336], gi\|1...	234.0	[0..9]	[312..1]

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Predicted Domain #1

Region A:
Residues: [1-326]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRDRLKDPVK IFEINKGKRP VHIAAPMVRY SKLPFRQLVR DYNTDIVYTP MILAKEFLHP  60
   61 KGRYFDFSTN DADASLILQF GVDDPVILEK AAQLVGPYVD GIGINCGCPQ TWAIQEGIGS 120
  121 ALLDEPEKVH KLVRAVKSTL GESFCTEVKI RIAKDLNKTR HLMQVIEKSG ADIITVHGRT 180
  181 RQDRSSFPVN LDAIREVRPC VQIPVVANGD VKSLRKGLEI AKYTETQGIM SARGLLENPA 240
  241 LFAGYEETPW GCVERFLWYS TSYSLNFHLF YHHLTTMMGQ MTTKRERMTI PKDSFASVMD 300
  301 WLDEHFVVRR PDEPMFGESV LPCRRY

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	44.69897
Match:	1vhnA
Description:	Crystal structure of a putative flavin oxidoreductase with flavin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.94749091175302	bayes_pls_golite062009
tRNA dihydrouridine synthase activity	1.94490879164338	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-CH group of donors	0.876786102965635	bayes_pls_golite062009
oxidoreductase activity	0.80115790656025	bayes_pls_golite062009
nucleic acid binding	0.453918901387506	bayes_pls_golite062009
binding	0.256396206082349	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: