YRC Public Data Repository - Protein Structure Prediction

Protein:	apl2
Organism:	Schizosaccharomyces pombe
Length:	683 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for apl2.

Description	E-value	Query Range	Subject Range
gi\|114668034 - gi\|114668034\|ref\|XP_001174142.1\| PREDICTED: adaptor-related protein complex 2, beta 1 subunit isofor...	470.0	[0..5]	[683..1]
AP2B1 - adaptor-related protein complex 2, beta 1 subunit gi\|149724034 - gi\|149724034\|ref\|XP_001503976.1\| PREDICTED: similar to beta-chain clathrin associated protein comple... AP2B1_RAT - AP-2 complex subunit beta OS=Rattus norvegicus GN=Ap2b1 PE=1 SV=1 gi\|73966773 - gi\|73966773\|ref\|XP_867698.1\| PREDICTED: similar to Adapter-related protein complex 2 beta 1 subunit ... gi\|114668040, gi... - gi\|114668042\|ref\|XP_001174162.1\| PREDICTED: adaptor-related protein complex 2, beta 1 subunit isofor... gi\|168277614 - gi\|168277614\|dbj\|BAG10785.1\| AP-2 complex subunit beta-1 [synthetic construct]	467.0	[0..5]	[683..1]
AP2B1_MOUSE - AP-2 complex subunit beta OS=Mus musculus GN=Ap2b1 PE=1 SV=1	467.0	[0..5]	[683..1]
gi\|73966787 - gi\|73966787\|ref\|XP_867764.1\| PREDICTED: similar to Adapter-related protein complex 2 beta 1 subunit ...	464.0	[0..5]	[683..1]

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Predicted Domain #1

Region A:
Residues: [1-584]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVPKLFQSSR FKAFKKSETS ELQKGLVSQY AYERIDAVKR TIAAMTVGKD VSSLFPDVLK  60
   61 NLATRDITLK KLVYLYLINY AKTHPDLCIL AVNTFVKDSE EYNPTLRALA IRTMGCIRVN 120
  121 KIIGYLADPL RKALKDEHPY VRKAAAVCVV KMYDLDREYC ASNGFIEQLQ ALVSDPNPVV 180
  181 VANAVRSLAE IHDQDPEKGY FNVVYTMTDR LMVALSECNE WGRITILNSL ARFRTSDIKE 240
  241 AEYVCERVVP QFQHANSGVV LSAVKVIMVH IPLFSSDFTD FLYKKMAPPL LTLLSTDSEI 300
  301 QYVALRNINL ILQKRPSIFD VKTRVFFCKY NDPLYIKMEK LKIITMLACD ENINETISEL 360
  361 RAYVSEVELE FVKQTIKCLG DVALKVPSVI NDCISIFLEI YELNISYMVQ EVTVVMETVL 420
  421 RKYPQKIDLL LPYLSRVIEE LGDPRARSSM AWILGEFSHV IPTSSKLLSE MISTMADEDL 480
  481 QIQLALLTAV VKLSLMNGKG NDEELVQKVL NYAINQSSNQ DLRDRAFAYQ RLLTPENVRK 540
  541 AQKIVCCEKP SVSYNNNLPE ALLDALLCEI TTLASVYHKL PESF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	109.0
Match:	1w63B
Description:	AP1 clathrin adaptor core
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [585-683]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IGQGKFGADA IQRRAVEELN IEEANVHEAI EKGANVENLL DLDFTDPGAT SASDSPITSA  60
   61 QPQSGSNSAM DLFMAFEAPS TNNAEPVKAR SATDDLLGL

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits