YRC Public Data Repository - Protein Structure Prediction

Protein:	vac8
Organism:	Schizosaccharomyces pombe
Length:	550 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for vac8.

Description	E-value	Query Range	Subject Range
gi\|111061218 - gi\|111061218\|gb\|EAT82338.1\| hypothetical protein SNOG_10003 [Phaeosphaeria nodorum SN15]	248.0	[0..9]	[545..17]
gi\|159126974 - gi\|159126974\|gb\|EDP52090.1\| vacuolar armadillo repeat protein Vac8, putative [Aspergillus fumigatus ... VAC8_ASPFU - Vacuolar protein 8 OS=Aspergillus fumigatus GN=vac8 PE=3 SV=1 VAC8_ASPFU - Vacuolar protein 8 OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) ...	239.0	[0..20]	[545..41]
gi\|115399484, gi... - gi\|115399484\|ref\|XP_001215331.1\| vacuolar protein 8 [Aspergillus terreus NIH2624], gi\|114192214\|gb\|E...	239.0	[0..20]	[545..41]
VAC8_CHAGB - Vacuolar protein 8 OS=Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NR... VAC8_CHAGB - Vacuolar protein 8 OS=Chaetomium globosum GN=VAC8 PE=3 SV=3	238.0	[0..1]	[546..1]
gi\|25314874, gi\|... - gi\|2959322\|emb\|CAA74966.1\| Importin alpha-like protein [Arabidopsis thaliana], pir\|\|T52101 probable ...	238.0	[0..2]	[454..10]
VAC8_ASPOR - Vacuolar protein 8 OS=Aspergillus oryzae (strain ATCC 42149 / RIB 40) GN=vac8 PE=3 SV=1 VAC8_ASPOR - Vacuolar protein 8 OS=Aspergillus oryzae GN=vac8 PE=3 SV=1 gi\|238500151, gi... - gi\|238500151\|ref\|XP_002381310.1\| vacuolar armadillo repeat protein Vac8, putative [Aspergillus flavu...	237.0	[0..20]	[545..41]
IMA1_MOUSE - Importin subunit alpha-1 OS=Mus musculus GN=Kpna2 PE=1 SV=2 gi\|53733645 - gb\|AAH83956.1\| Unknown (protein for MGC:97971) [Xenopus laevis]	235.0	[0..2]	[453..21]
VAC8_YARLI - Vacuolar protein 8 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=VAC8 PE=3 SV=1 VAC8_YARLI - Vacuolar protein 8 OS=Yarrowia lipolytica GN=VAC8 PE=3 SV=1	235.0	[0..18]	[522..41]

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Predicted Domain #1

Region A:
Residues: [1-550]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGNCLSCCEK SKDEQYEPLL ADREREAVAD LLSFLEDRNE VNFYSEEPLR ALTILAYSDN  60
   61 LDLQRSAALA FAEITEKDVR EVDRETIEPV LFLLQSPDAE IQRAASVALG NLAVNAENKA 120
  121 LVVKLNGLDL LIRQMMSPHV EVQCNAVGCI TNLATLDENK SKIAHSGALG PLTRLAKSKD 180
  181 IRVQRNATGA LLNMTHSYEN RQQLVSAGTI PVLVSLLPSS DTDVQYYCTT SISNIAVDAV 240
  241 HRKRLAQSEP KLVRSLIQLM DTSSPKVQCQ AALALRNLAS DERYQIEIVQ SNALPSLLRL 300
  301 LRSSYLPLIL ASVACIRNIS IHPLNESPII DAGFLRPLVD LLSCTENEEI QCHAVSTLRN 360
  361 LAASSERNKR AIIEANAIQK LRCLILDAPV SVQSEMTACL AVLALSDEFK SYLLNFGICN 420
  421 VLIPLTDSMS IEVQGNSAAA LGNLSSNVDD YSRFIECWDS PAGGIHGYLV RFLSSEDSTF 480
  481 AHIAAWTIVQ LLEAGVPRLT AFIQSSDDII ELLNDIVARD ANNGEYEDGE GDVILLSGRA 540
  541 LHLIEQDTDS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	44.69897
Match:	1jpwA
Description:	beta-Catenin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
protein transporter activity	3.09219467906677	bayes_pls_golite062009
binding	2.48958374349477	bayes_pls_golite062009
transporter activity	2.48700774379895	bayes_pls_golite062009
substrate-specific transporter activity	2.01243877392722	bayes_pls_golite062009
protein binding	1.94427330399472	bayes_pls_golite062009
clathrin binding	1.82663703481803	bayes_pls_golite062009
transmembrane transporter activity	1.28481004323799	bayes_pls_golite062009
protein transmembrane transporter activity	1.27438167414302	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	0.851483195437252	bayes_pls_golite062009
nuclear localization sequence binding	0.661470469730249	bayes_pls_golite062009
hydrolase activity	0.610187344532862	bayes_pls_golite062009
signal sequence binding	0.57106697498903	bayes_pls_golite062009
active transmembrane transporter activity	0.252495966234234	bayes_pls_golite062009
primary active transmembrane transporter activity	0.00492507437049428	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: