YRC Public Data Repository - Protein Structure Prediction

Protein:	sec11
Organism:	Schizosaccharomyces pombe
Length:	189 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for sec11.

Description	E-value	Query Range	Subject Range
gi\|114658678 - gi\|114658678\|ref\|XP_510560.2\| PREDICTED: similar to SPC18 protein [Pan troglodytes]	216.0	[0..1]	[173..188]
gi\|34784421 - gi\|34784421\|gb\|AAH57885.1\| Sec11a protein [Mus musculus]	210.0	[0..1]	[187..106]
gi\|109082238 - gi\|109082238\|ref\|XP_001084602.1\| PREDICTED: similar to Microsomal signal peptidase 18 kDa subunit (S...	206.0	[0..1]	[173..136]
gi\|195568779, gi... - gi\|195568779\|ref\|XP_002102391.1\| GD19887 [Drosophila simulans], gi\|194198318\|gb\|EDX11894.1\| GD19887 ... gi\|220942718 - gi\|220942718\|gb\|ACL83902.1\| Spase18-21-PA [synthetic construct] gi\|195344031, gi... - gi\|195344031\|ref\|XP_002038594.1\| GM10908 [Drosophila sechellia], gi\|194133615\|gb\|EDW55131.1\| GM10908... gi\|195498966, gi... - gi\|195498966\|ref\|XP_002096749.1\| GE24877 [Drosophila yakuba], gi\|194182850\|gb\|EDW96461.1\| GE24877 [D... gi\|190650805, gi... - gi\|194899103\|ref\|XP_001979102.1\| GG13600 [Drosophila erecta], gi\|190650805\|gb\|EDV48060.1\| GG13600 [D... Spase18-21-PA - The gene Spase 18/21-subunit is referred to in FlyBase by the symbol Dmel\Spase18-21 (CG2358, FBgn00...	203.0	[0..2]	[187..17]
gi\|54638969\|gb\|E... - GA15357-PA [Drosophila pseudoobscura], GA15357 [Drosophila pseudoobscura pseudoobscura] gi\|194112038, gi... - gi\|195152113\|ref\|XP_002016981.1\| GL21767 [Drosophila persimilis], gi\|194112038\|gb\|EDW34081.1\| GL2176... gi\|54638969, gi\|... - gi\|54638969\|gb\|EAL28371.1\| GA15357 [Drosophila pseudoobscura pseudoobscura], gi\|125776277\|ref\|XP_001...	203.0	[0..2]	[187..17]
gi\|86438376, gi\|... - gi\|86438376\|gb\|AAI12784.1\| SEC11 homolog C (S. cerevisiae) [Bos taurus], gi\|115496204\|ref\|NP_0010686...	203.0	[0..1]	[187..22]
gi\|194214714 - gi\|194214714\|ref\|XP_001489335.2\| PREDICTED: similar to Signal peptidase complex catalytic subunit SE... tr\|M3W609\|M3W609... - Signal peptidase complex catalytic subunit SEC11 OS=Felis catus GN=SEC11C PE=3 SV=1 SC11C_CANLF - Signal peptidase complex catalytic subunit SEC11C OS=Canis lupus familiaris GN=SEC11C PE=1 SV=3	203.0	[0..1]	[187..22]
SEC11C - SEC11 homolog C (S. cerevisiae) SC11C_PONAB - Signal peptidase complex catalytic subunit SEC11C OS=Pongo abelii GN=SEC11C PE=2 SV=3 SC11C_PONPY, SPC... - Microsomal signal peptidase 21 kDa subunit (EC 3.4.-.-) (SPase 21 kDa subunit) (SPC21) (SEC11-like 3...	203.0	[0..1]	[187..22]

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Predicted Domain #1

Region A:
Residues: [1-189]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQKLSFRQGL AQILNLLLVL SSAYMGYKTL SFVTDCESPV VVVLSESMEP SFQRGDLLFL  60
   61 DNRNPSFDEA KVPSVFEKII YGSPVGIGDI VVYSLPDRPI PIVHRVVKLY ESENQTHLIT 120
  121 KGDNNKIDDV AMFPKSINYL DRENHILGVV RGYFPYLGMI TIWLTDYPIL KYIMLGGLGL 180
  181 LTLIQKEEQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	10.39794
Match:	1b12A
Description:	Type 1 signal peptidase
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits