YRC Public Data Repository - Protein Structure Prediction

Protein:	lsk1
Organism:	Schizosaccharomyces pombe
Length:	593 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for lsk1.

Description	E-value	Query Range	Subject Range
gi\|8132287 - gi\|8132287\|gb\|AAF73236.1\|AF153061_1 MAP kinase 3 [Pisum sativum]	305.0	[0..251]	[592..13]
gi\|92700087, gi\|... - gi\|92700087\|dbj\|BAB18271.2\| mitogen-activated protein kinase [Chlamydomonas reinhardtii], gi\|1594844...	304.0	[0..255]	[585..36]
gi\|92885696 - gi\|92885696\|gb\|ABE87884.1\| Serine/threonine protein kinase, active site [Medicago truncatula]	304.0	[0..251]	[592..13]
gi\|1667373, gi\|7... - pir\|\|T09622 protein kinase MMK4 (EC 2.7.1.-), cold- and drought-induced - alfalfa, gi\|1667373\|emb\|CA...	304.0	[0..251]	[592..13]
gi\|33337696 - gi\|33337696\|gb\|AAQ13491.1\|AF104247_1 mitogen-activated protein kinase 1 [Glycine max]	302.0	[0..251]	[592..13]
gi\|254839180, gi... - gi\|93278865\|pdb\|2BKZ\|C Chain C, Structure Of Cdk2-Cyclin A With Pha-404611, gi\|93278863\|pdb\|2BKZ\|A C...	302.0	[0..272]	[578..4]
gi\|117499872 - gi\|117499872\|gb\|ABK34941.1\| cyclin-dependent kinase 2 [Capra hircus] gi\|215983068, gi... - gi\|215983068\|ref\|NP_001135981.1\| cyclin-dependent kinase 2 [Ovis aries], gi\|213688920\|gb\|ACJ53943.1\|... CDK2_BOVIN - Cyclin-dependent kinase 2 OS=Bos taurus GN=CDK2 PE=2 SV=1	301.0	[0..274]	[567..1]
CDK2_RAT - Cyclin-dependent kinase 2 OS=Rattus norvegicus GN=Cdk2 PE=1 SV=1 gi\|710025 - gi\|710025\|dbj\|BAA05947.1\| cyclin dependent kinase 2-alpha [Rattus rattus]	301.0	[0..274]	[567..1]
gi\|10862876 - gi\|10862876\|emb\|CAC13967.1\| MAPK2 protein [Oryza sativa]	301.0	[0..251]	[593..10]

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Predicted Domain #1

Region A:
Residues: [1-193]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSYSKSTIYR RQGTEPNSHF RRTVEEKSQL SGTNEESLGG HTLSSNAFKN NSSSISPSSS  60
   61 AKDPREQRKR TFPLNDTHSS RARQHERPFR SRKSRRRKGK KAFSPRPGSP PSPSFYRSGS 120
  121 QKRARNLTTK DYFAKRSESS SSASVSPISP SANRNDSKRQ ASSFRRSPPS SVHMKPSAFN 180
  181 GRKVSRRPSS SPP

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [194-528]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PIPSIPHETT SSDTQKKSSV SSGFPENKHG KFHFHIPNER RSRFDQPPSK RMALTSTARE  60
   61 SVPAPLPSPP SGPIYTYTYP KPAYEKIDQI GEGTYGKVYK AINTVTGDLV ALKRIRLEQE 120
  121 KDGFPITTVR EVKILQRLRH KNIVRLLEIM VEKSSVYMVF EYMDHDLTGV LLNSQLHFTP 180
  181 GNIKHLSKQI FEALAYLHHR GVLHRDIKGS NILLNNNGDL KFADFGLARF NTSSKSANYT 240
  241 NRVITLWFRP PELLLGETAY DTAVDIWSAG CIVMELFTGK PFFQGRDEIS QLEVIYDMMG 300
  301 TPDVHSWPEV KNLPWYELLK PVEEKKSRFV ETFKE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	41.0
Match:	2ozoA
Description:	No description for 2ozoA was found.

Predicted Domain #3

Region A:
Residues: [529-593]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ILSPAAIDLC QKLLALNPFC RPSAHETLMH EYFTSESPPP EPAVILKNMQ GSWHEWESKK  60
   61 RKSKR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	81.69897
Match:	1vywA
Description:	Structure of CDK2/Cyclin A with PNU-292137
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits