YRC Public Data Repository - Protein Structure Prediction

Protein:	npl4
Organism:	Schizosaccharomyces pombe
Length:	545 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for npl4.

Description	E-value	Query Range	Subject Range
gi\|39944862, gi\|... - gi\|39944862\|ref\|XP_361968.1\| hypothetical protein MG04413.4 [Magnaporthe grisea 70-15], gb\|EAA50654....	786.0	[0..1]	[540..1]
NPL4_NEUCR - Nuclear protein localization protein 4 OS=Neurospora crassa GN=npl-4 PE=3 SV=1 NPL4_NEUCR - Nuclear protein localization protein 4 OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 70...	766.0	[0..1]	[540..1]
gi\|42544756, gi\|... - gi\|46108668\|ref\|XP_381392.1\| hypothetical protein FG01216.1 [Gibberella zeae PH-1], gi\|42544756\|gb\|E...	761.0	[0..1]	[540..1]
gi\|148702797, gi... - gi\|37360414\|dbj\|BAC98185.1\| mKIAA1499 protein [Mus musculus], gi\|148702797\|gb\|EDL34744.1\| nuclear pr...	747.0	[0..1]	[539..59]
gi\|147898562, gi... - gi\|33585642\|gb\|AAH56013.1\| Npl4 protein [Xenopus laevis], gi\|147898562\|ref\|NP_001080427.1\| homolog o...	746.0	[0..1]	[539..5]
NPLOC4 - nuclear protein localization 4 homolog (S. cerevisiae) gi\|123997361 - gi\|123997361\|gb\|ABM86282.1\| nuclear protein localization 4 homolog (S. cerevisiae) [synthetic constr...	744.0	[0..1]	[539..5]
gi\|73964791 - gi\|73964791\|ref\|XP_540482.2\| PREDICTED: similar to NPL4 protein [Canis familiaris]	742.0	[0..2]	[539..13]
NPL4_RAT - Nuclear protein localization protein 4 homolog OS=Rattus norvegicus GN=Nploc4 PE=1 SV=3	742.0	[0..1]	[539..5]

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Predicted Domain #1

Region A:
Residues: [1-140]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MILRFRSKRG MARAEFQPTD TLAMLSAKIL SDILKNDYSP ENVSLCQNES DQGVIFSNLN  60
   61 DQTLQDAGLT HGQMLYLRLG TPNSDIASSN NEPALTVTGA PKQVSTPDVS EKKPSMPVIQ 120
  121 DPIDDSLEKE DGLIRRSMTS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	17.0
Match:	2pjhA
Description:	No description for 2pjhA was found.

Predicted Domain #2

Region A:
Residues: [141-191]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LCRHGPKGMC DYCSPLEPYD ESYRQENKIK HLSFHAYLRK INSNVNKYAS S

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [192-483]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QSFIPPLEEP SFTVKEKCPS GHPPWPAGIC TKCQPSTVML NLQPFRVIDH IEFASPGIVD  60
   61 SFLNKWRQSG FQRIGYTYGH FEQYNNVPLG IKGVIEAIYE PPQVSEADGV TLEEWADEAL 120
  121 VEQVATACGL RRIGIIFTDL TDDGSNSGKV LCKRHSDSYF LSSLEVYNSA NFQTKFKNPC 180
  181 KWSRSGYFGS KFVTSVISGN LNGEIEVMSY QVSNIGTALY QADLIQPSVD PDRMLVKKED 240
  241 QTRYVPDVLY RYTDKYGKQV SENAKPAFPV SFLLVTLTDG FPEKPDPLFS NN

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	2.89
Match:	2og4A
Description:	No description for 2og4A was found.

Predicted Domain #4

Region A:
Residues: [484-545]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DTSIITTLES TDETGRLRQL AKLFDHNAIA NGSLSNFSVL LAIAKLSILG KVSIIIYFFY  60
   61 MY

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits