YRC Public Data Repository - Protein Structure Prediction

Protein:	SPBC36B7.04
Organism:	Schizosaccharomyces pombe
Length:	399 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBC36B7.04.

Description	E-value	Query Range	Subject Range
DUS1L - dihydrouridine synthase 1-like (S. cerevisiae)	289.0	[0..5]	[388..3]
gi\|114671084, gi... - gi\|114671086\|ref\|XP_001167386.1\| PREDICTED: PP3111 protein isoform 2 [Pan troglodytes], gi\|114671084...	288.0	[0..5]	[387..3]
DUS1L_MOUSE - tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like OS=Mus musculus GN=Dus1l PE=2 SV=1	284.0	[0..5]	[388..3]
gi\|73964669 - gi\|73964669\|ref\|XP_848227.1\| PREDICTED: similar to PP3111 protein isoform 2 [Canis familiaris]	283.0	[0..5]	[388..3]
DUS1_YEAST - tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)] OS=Saccharomyces cerevisiae (strain ATCC 204508 / S2... DUS1 - Dihydrouridine synthase, member of a widespread family of conserved proteins including Smm1p, Dus3p,...	283.0	[0..5]	[393..16]
gi\|46436256, gi\|... - gi\|68483082\|ref\|XP_714575.1\| likely tRNA dihydrouridine synthase [Candida albicans SC5314], gi\|68482... orf19.1404, orf1... - orf19.1404 CGDID:CAL0004455 Assembly 19, Contig19-10113 (97371, 95968) CDS, reverse complemented, tr... gi\|238883810 - gi\|238883810\|gb\|EEQ47448.1\| tRNA-dihydrouridine synthase 1 [Candida albicans WO-1]	283.0	[0..3]	[395..43]
gi\|37589069, gi\|... - gi\|41054535\|ref\|NP_955911.1\| dihydrouridine synthase 1-like [Danio rerio], gi\|37589069\|gb\|AAH58873.1...	279.0	[0..1]	[391..1]
DUS1L_RAT - tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like OS=Rattus norvegicus GN=Dus1l PE=2 SV=1	277.0	[0..5]	[388..3]

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Predicted Domain #1

Region A:
Residues: [1-399]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASKKLHGRD FYNKIGRPKR ILAPMVDQSE LPWRILARRS GADLCYSPMF HSRLFGESED  60
   61 YRNKVFSTRT IPEERPLIIQ FCGNDPEIML KAAKIAAPYC DAVDVNLGCP QGIAKKGKYG 120
  121 SFLQENWNLI ESIITKLHTE LSIPVTAKIR IFPDPQKTLD YAKMILKAGA SILAVHGRLR 180
  181 EQKGHFTGIA DWEQIQMLRK NLPSETVLFA NGNILHAQDI DRCIKYTGVD GVLSAEGSLY 240
  241 NPRIFLPPSS PLMTLYPRID DMCEEYLNII REFKLESDYS SLSAIKGHLF KLMRPLLSIH 300
  301 TDIRSKLAQG CTPRDFETFP PVVAMLRKRL LECEEKGEIN EDKDVKESVK DSMGYPVIPW 360
  361 WRVQPYIRPL EVPLVTKRKP VEVTADEGPV KKKVNASVA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	53.0
Match:	1vhnA
Description:	Crystal structure of a putative flavin oxidoreductase with flavin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.94749091175302	bayes_pls_golite062009
tRNA dihydrouridine synthase activity	1.94490879164338	bayes_pls_golite062009
nucleic acid binding	1.03692680161964	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-CH group of donors	0.876786102965635	bayes_pls_golite062009
oxidoreductase activity	0.80115790656025	bayes_pls_golite062009
binding	0.68572942532795	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: