YRC Public Data Repository - Protein Structure Prediction

Protein:	prp12
Organism:	Schizosaccharomyces pombe
Length:	1206 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for prp12.

Description	E-value	Query Range	Subject Range
gi\|114663425 - gi\|114663425\|ref\|XP_511081.2\| PREDICTED: similar to KIAA0017 protein [Pan troglodytes]	1532.0	[0..7]	[1204..67]
gi\|40788938 - gi\|40788938\|dbj\|BAA32662.2\| KIAA0017 protein [Homo sapiens]	1525.0	[0..6]	[1204..36]
gi\|73957045 - gi\|73957045\|ref\|XP_536791.2\| PREDICTED: similar to splicing factor 3b, subunit 3 isoform 1 [Canis fa... gi\|149699332 - gi\|149699332\|ref\|XP_001500880.1\| PREDICTED: similar to Splicing factor 3B subunit 3 (Spliceosome-ass...	1520.0	[0..7]	[1204..1]
tr\|G3HAF4\|G3HAF4... - Splicing factor 3B subunit 3 OS=Cricetulus griseus GN=I79_007403 PE=4 SV=1 tr\|E9PT66\|E9PT66_RAT - Protein Sf3b3 OS=Rattus norvegicus GN=Sf3b3 PE=4 SV=2 SF3B3_MOUSE - Splicing factor 3B subunit 3 OS=Mus musculus GN=Sf3b3 PE=1 SV=1	1520.0	[0..7]	[1204..1]
SF3B3_PONAB - Splicing factor 3B subunit 3 OS=Pongo abelii GN=SF3B3 PE=2 SV=1 SF3B3_PONPY - Splicing factor 3B subunit 3 - Pongo pygmaeus (Orangutan)	1513.0	[0..7]	[1204..1]
SF3B3_DANRE - Splicing factor 3B subunit 3 OS=Danio rerio GN=sf3b3 PE=2 SV=1	1500.0	[0..7]	[1204..1]

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Predicted Domain #1

Region A:
Residues: [1-1206]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDTFPSLFLY SLTIQNSNYV QSSCAASLSG KKAQEIVIAT ESRLLIYKVD ATDGRMNCIL  60
   61 NQNCFGIIRN VAPLRLTGFK RDYLVVTSDS GRITILEYNV EKNKLVPIYQ ETFGKSGIRR 120
  121 VVPGEYLAID AKGRAAMIAS VEKNKLVYVL NRDSEANLTI SSPLEAHKAN NICFHLIGLD 180
  181 TGYANPIFAA LEVDYSEIDH DSTREAFTSS EKVLSYYELD LGLNHVVKRW SKVVDRNSYM 240
  241 LIPVPGGNDG PSGTLVISNG WISYRHLQKA FHQIPILRRQ AASANAISTP WNQVNSNSAN 300
  301 DGPLIVSAVL HKMKGSFFYL LQTGDGDLLK LTIEHDGQGN VVELRLKYFD TVPLAVQLNI 360
  361 LKTGFLFVAT EFGNHQLYQF ENLGIDDDEL EITSLDFQAQ DNEVGTKNVH FGVRGLQNLS 420
  421 LVEEIPSLYS LTDTLLMKAP SSGEANQLYT VCGRGSNSSL RQLRRGLETT EIVASELPGA 480
  481 PIAIWTLKLN QTDVYDSYII LSFTNGTLVL SIGETVEEIS DSGFLSSVST LNARQMGRDS 540
  541 LVQIHPKGIR YIRANKQTSE WKLPQDVYVV QSAINDMQIV VALSNGELVY FEMSDDVEGG 600
  601 QLNEYQERKT LTANVTSLAL GPVQEGSRRS NFMCLACDDA TVRVLSLDLY TTLENLSVQA 660
  661 LSSPANSLCI IPMNVNGVST LYLHIGLMNG VYLRTVIDVT SGQLLDTRTR FLGPRAVKIY 720
  721 PITMKNQNTV LAVSSRTFLA YSYQQNLQLS PIAYSAIDHA SSFASEQCPE GIVAIQKNTL 780
  781 KIFTVDSLQD DLKSDIYPLI CTPRKIVKHP NFPVLYILQS ERNFDSFKYA QENGDVGSSY 840
  841 TKEKQNEHTS KSWVSFISVF DMISKKIIHE SPLGDNEAAF SMTAAFFKNR DEFFLVAGSA 900
  901 TNMDLECRTC SHGNFRVYRF HDEGKKLELI SHTEIDGIPM ALTPFQGRML AGVGRFLRIY 960
  961 DLGNKKMLRK GELSAVPLFI THITVQASRI VVADSQYSVR FVVYKPEDNH LLTFADDTIH1020
 1021 RWTTTNVLVD YDTLAGGDKF GNIWLLRCPE HVSKLADEEN SESKLIHEKP FLNSTPHKLD1080
 1081 LMAHFFTNDI PTSLQKVQLV EGAREVLLWT GLLGTVGVFT PFINQEDVRF FQQLEFLLRK1140
 1141 ECPPLAGRDH LAYRSYYAPV KCVIDGDLCE MYYSLPHPVQ EMIANELDRT IAEVSKKIED1200
 1201 FRVRSF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1000.0
Match:	2b5lA
Description:	Crystal Structure of DDB1 In Complex with Simian Virus 5 V Protein
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits