YRC Public Data Repository - Protein Structure Prediction

Protein:	pep12
Organism:	Schizosaccharomyces pombe
Length:	317 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for pep12.

Description	E-value	Query Range	Subject Range
gi\|109099266 - gi\|109099266\|ref\|XP_001111568.1\| PREDICTED: similar to syntaxin 2 isoform 2 [Macaca mulatta]	163.0	[0..16]	[264..131]
gi\|50759625 - gi\|50759625\|ref\|XP_417710.1\| PREDICTED: similar to guanylate binding protein [Gallus gallus]	149.0	[0..23]	[260..1078]
gi\|73958357 - gi\|73958357\|ref\|XP_547038.2\| PREDICTED: similar to Syntaxin-1B2 (Syntaxin 1B) (P35B) [Canis familiar...	145.0	[0..11]	[242..39]
gi\|220777, gi\|285304 - pir\|\|A38141 neuronal cell membrane antigen HPC-1 - rat (fragment), gi\|220777\|dbj\|BAA01231.1\| HPC-1 ...	135.0	[0..11]	[261..42]
gi\|114613937 - gi\|114613937\|ref\|XP_001146812.1\| PREDICTED: hypothetical protein isoform 2 [Pan troglodytes]	134.0	[0..11]	[256..32]
gi\|94375456 - gi\|94375456\|ref\|XP_921129.2\| PREDICTED: similar to Epimorphin (Syntaxin-2) [Mus musculus]	134.0	[0..45]	[243..187]
gi\|303605 - gi\|303605\|dbj\|BAA03436.1\| epimorphin [Homo sapiens]	133.0	[0..12]	[260..32]

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Predicted Domain #1

Region A:
Residues: [1-317]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFVDLEQGR HKIEQNGDFP ALASSIAQEI HALRGNTAAI HRYLVNNLTK NLHEVLEQSR  60
   61 ELSQKVRSDL VRLANIKDTK YGEEASSFAL SKLTRDFNTV LAELQRVQQK CAQQESDSVA 120
  121 AAQAALNQDV GQHFIEEEER NVSLSNNSSG QRQPLTESKI SNSQLEYQQR LINERQGEIE 180
  181 NLTQGINELN EIFRDLSTII NEQGELVTNI EYNVGNTSTN TKNASRQLQI ANEHSRKARK 240
  241 RSFCFLKSFA MFSSFRSQNA NLYNLNSIRR NLTKHFRNRV LVSLYVSCSS RVWSLPYVHA 300
  301 FKIAYSIQFL DTDYFFT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	23.154902
Match:	1dn1B
Description:	Syntaxin 1A N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
SNAP receptor activity	2.83778981988519	bayes_pls_golite062009
protein binding	2.01524199895183	bayes_pls_golite062009
binding	1.88170908543488	bayes_pls_golite062009
protein transporter activity	0.928646845054548	bayes_pls_golite062009
transporter activity	0.487715383686856	bayes_pls_golite062009
SNARE binding	0.44377480710212	bayes_pls_golite062009
substrate-specific transporter activity	0.0443963926233321	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: