YRC Public Data Repository - Protein Structure Prediction

Protein:	SPAC23G3.05c
Organism:	Schizosaccharomyces pombe
Length:	343 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAC23G3.05c.

Description	E-value	Query Range	Subject Range
gi\|46109242, gi\|... - gi\|46109242\|ref\|XP_381679.1\| hypothetical protein FG01503.1 [Gibberella zeae PH-1], gi\|42546045\|gb\|E...	375.0	[0..5]	[343..25]
gi\|49092596, gi\|... - gi\|67526329\|ref\|XP_661226.1\| hypothetical protein AN3622.2 [Aspergillus nidulans FGSC A4], ref\|XP_40...	349.0	[0..5]	[343..16]
gi\|85117392 - gi\|85117392\|ref\|XP_965246.1\| hypothetical protein NCU08343 [Neurospora crassa OR74A] gi\|28927052, gi\|... - gi\|32417822\|ref\|XP_329389.1\| hypothetical protein [Neurospora crassa], gi\|28927052\|gb\|EAA36010.1\| co...	344.0	[0..5]	[343..21]
gi\|38105741, gi\|... - gi\|39943292\|ref\|XP_361183.1\| hypothetical protein MG03726.4 [Magnaporthe grisea 70-15], gb\|EAA52131....	337.0	[0..5]	[343..21]
gi\|115389642, gi... - gi\|115389642\|ref\|XP_001212326.1\| conserved hypothetical protein [Aspergillus terreus NIH2624], gi\|11...	337.0	[0..5]	[343..16]
gi\|83764660 - gi\|83764660\|dbj\|BAE54804.1\| unnamed protein product [Aspergillus oryzae] gi\|169764669 - gi\|169764669\|ref\|XP_001816806.1\| hypothetical protein [Aspergillus oryzae RIB40] gi\|238504070, gi... - gi\|238504070\|ref\|XP_002383267.1\| RGS domain protein (Rax1), putative [Aspergillus flavus NRRL3357], ...	331.0	[0..5]	[343..16]
RAX1_YEAST - Bud site selection protein RAX1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RAX1 PE=... RAX1 - Protein involved in bud site selection during bipolar budding; localization requires Rax2p; has simi...	319.0	[0..5]	[342..23]
gi\|119192426, gi... - gi\|90305605\|gb\|EAS35236.1\| hypothetical protein CIMG_00590 [Coccidioides immitis RS], gi\|119192426\|r...	314.0	[0..5]	[343..17]
gi\|159125503 - gi\|159125503\|gb\|EDP50620.1\| RGS domain protein (Rax1), putative [Aspergillus fumigatus A1163] gi\|70993440, gi\|... - gi\|70993440\|ref\|XP_751567.1\| RGS domain protein (Rax1) [Aspergillus fumigatus Af293], gi\|66849201\|gb...	309.0	[0..5]	[343..16]
gi\|44985125 - gi\|44985125\|gb\|AAS53903.1\| AFR532Wp [Ashbya gossypii ATCC 10895] gi\|44985125, gi\|... - gi\|45199050\|ref\|NP_986079.1\| AFR532Wp [Ashbya gossypii ATCC 10895], gi\|44985125\|gb\|AAS53903.1\| AFR53...	305.0	[0..5]	[343..14]

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Predicted Domain #1

Region A:
Residues: [1-60]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASAPRVSEV LTKKNLPPLS LYNFYIYIRD EENAIEFLDL FLDIMLHKFL FREHIRGLYK  60
   61

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [61-226]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AGVTSTSLNT ESSSTLGPHH FTRFRSASLS LEDLSTVYWP NFGPLLLEEL SNEQTINSSD  60
   61 LLLSKDRAAY LKNLLTSNIQ SLTQESTVIS KEQVKMFTQI IIEKYFNPAS PHEVMLPPQL 120
  121 VQPILDCKEH QRQDELRLFE DVETYLLNFL LKPAYYRFLN HKFKHN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	35.69897
Match:	1agrE
Description:	Regulator of G-protein signalling 4, RGS4
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	1.77517709802718	bayes_pls_golite062009
protein binding	1.37097137655743	bayes_pls_golite062009
nucleoside-triphosphatase regulator activity	1.13899380938509	bayes_pls_golite062009
GTPase regulator activity	1.11716566045476	bayes_pls_golite062009
enzyme regulator activity	0.930307440055454	bayes_pls_golite062009
GTPase activator activity	0.845105141539921	bayes_pls_golite062009
enzyme activator activity	0.830104847091967	bayes_pls_golite062009

Predicted Domain #3

Region A:
Residues: [227-343]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LNPLTCTGRF IIGYVSTFAA YWLGFCGIFL DYSRRKRVWT LLPFAFGFYN LICTWSKHDP  60
   61 VLALLGYSEV KPFHYEKVLQ PSIRLSLNRR AIFVLSIIVL IVGANTAIFS CVPSIRL

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: