YRC Public Data Repository - Protein Structure Prediction

Protein:	pvg2
Organism:	Schizosaccharomyces pombe
Length:	389 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for pvg2.

Description	E-value	Query Range	Subject Range
OCH1_CANAL - Initiation-specific alpha-1,6-mannosyltransferase OS=Candida albicans (strain SC5314 / ATCC MYA-2876... gi\|238881006 - gi\|238881006\|gb\|EEQ44644.1\| hypothetical protein CAWG_02918 [Candida albicans WO-1] orf19.7391 - OCH1 CGDID:CAL0004830 Assembly 19, Contig19-2513 (118280, 117123) CDS, reverse complemented, transla...	251.0	[0..11]	[347..11]
gi\|17978673 - gi\|17978673\|gb\|AAL49987.1\| putative mannosyltransferase [Candida albicans]	251.0	[0..11]	[337..11]
gi\|49650982, gi\|... - gi\|49650982\|emb\|CAG77919.1\| YALI0F07260p [Yarrowia lipolytica], gi\|38488500\|emb\|CAD91643.1\| alpha 1,... gi\|49650982, gi\|... - gi\|50555407\|ref\|XP_505112.1\| YALI0F07260p [Yarrowia lipolytica], gi\|49650982\|emb\|CAG77919.1\| YALI0F0...	214.0	[0..13]	[337..11]
gi\|32446529, gi\|... - gi\|32475986\|ref\|NP_868980.1\| surface protein Sur1 [Rhodopirellula baltica SH 1], gi\|32446529\|emb\|CAD...	201.0	[0..121]	[341..3]
gi\|33331887 - gi\|33331887\|gb\|AAQ11191.1\| putative mannosyltransferase [Pichia angusta]	197.0	[0..46]	[283..79]
gi\|23002168 - gi\|23002168\|ref\|ZP_00045846.1\| hypothetical protein Lgas_03000149 [Lactobacillus gasseri ATCC 33323] gi\|23002168 - gi\|23002168\|ref\|ZP_00045846.1\| COG3774: Mannosyltransferase OCH1 and related enzymes [Lactobacillus ... gi\|227520740, gi... - gi\|227520740\|ref\|ZP_03950789.1\| glycosyltransferase [Lactobacillus gasseri JV-V03], gi\|227094594\|gb\|... gi\|226820627 - gi\|226820627\|ref\|ZP_03809746.1\| mannosyltransferase OCH1 related enzyme [Lactobacillus gasseri MV-22...	196.0	[0..121]	[343..3]
gi\|30409755 - gi\|30409755\|gb\|AAP32730.1\| EpsQ [Lactococcus lactis subsp. cremoris]	195.0	[0..121]	[340..2]
gi\|24637467 - gi\|24637467\|gb\|AAN63739.1\|AF454498_12 Eps7I [Streptococcus thermophilus]	193.0	[0..121]	[337..2]
gi\|90576964 - gi\|90576964\|gb\|ABD95555.1\| CpsM [Streptococcus agalactiae]	188.0	[0..121]	[339..2]

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Predicted Domain #1

Region A:
Residues: [1-389]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTKLWVNFFS QKLLRLLIPS IIVVFAFAAL FAIYSPIQLG GINFYKRTNL FTVEELGEKE  60
   61 LELSKTVTID IYRKAMCMDD LEQSRKCTTF GLDPPISAHL FYTYNRDTGM NRVARQWNRR 120
  121 IPRVFHTIKG SNFIELSQFT AFEVELRVSH PNWAFVSWSH DDLNELVDKS YHNLHNAWSQ 180
  181 LSREAKDQWG FLLGLYEYGG VWMSRSLQLK KNIDKFVYAA ELSVKQFTEN ITSSTVEEFQ 240
  241 PIFMAPKSLQ YDFMIATPKH PFVLSLINEL CKSEVLLKIL SKRPYHGLDA AEALFAENRE 300
  301 SITIREQEFF VNTYIDDGKV FVKNNPHIIF IPTEAFASTW DFLPSEESSE MCFADSPLFD 360
  361 PDYCISHSSK PDGNELAIYW SNSFDLITA

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.81
Match:	2bvlA
Description:	Crystal structure of the catalytic domain of toxin B from Clostridium difficile in complex with UDP, Glc and manganese ion
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transferase activity, transferring hexosyl groups	2.23446625487311	bayes_pls_golite062009
transferase activity	1.88507515835159	bayes_pls_golite062009
UDP-glycosyltransferase activity	1.84596125277114	bayes_pls_golite062009
catalytic activity	1.73979371332125	bayes_pls_golite062009
guanylyltransferase activity	1.04214021429109	bayes_pls_golite062009
nucleotidyltransferase activity	0.976685272456639	bayes_pls_golite062009
acetylgalactosaminyltransferase activity	0.823843077041128	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.800677969431881	bayes_pls_golite062009
uridylyltransferase activity	0.790072592167014	bayes_pls_golite062009
cytidylyltransferase activity	0.666765511953956	bayes_pls_golite062009
mannose-1-phosphate guanylyltransferase activity	0.625431872491814	bayes_pls_golite062009
polypeptide N-acetylgalactosaminyltransferase activity	0.600389101620522	bayes_pls_golite062009
binding	0.594806047305175	bayes_pls_golite062009
transferase activity, transferring glycosyl groups	0.539883035270389	bayes_pls_golite062009
mannosyltransferase activity	0.505948108814334	bayes_pls_golite062009
UDP-N-acetylglucosamine diphosphorylase activity	0.0309517682490415	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: