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View Structure Prediction Details

Protein: SPCC737.06c
Organism: Schizosaccharomyces pombe
Length: 287 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPCC737.06c.

Description E-value Query
Range
Subject
Range
gi|157104550, gi... - gi|157104558|ref|XP_001648465.1| aldo-keto reductase [Aedes aegypti], gi|157104556|ref|XP_001648464....
282.0 [0..2] [277..1]
gi|118777462, gi... - gi|118777462|ref|XP_308086.3| AGAP011050-PA [Anopheles gambiae str. PEST], gi|116132724|gb|EAA45511....
AGAP011050-PA - aldehyde reductase|protein_coding|3L:15774210:15776890:-1|gene:AGAP011050
279.0 [0..2] [277..1]
gi|91076412 - gi|91076412|ref|XP_969601.1| PREDICTED: similar to AGAP011050-PA [Tribolium castaneum]
279.0 [0..2] [277..1]
gi|66525576 - gi|66525576|ref|XP_624353.1| PREDICTED: similar to CG6084-PA, isoform A isoform 1 [Apis mellifera]
274.0 [0..1] [283..1]
gi|118403930, gi... - gi|118403930|ref|NP_001072181.1| 3-alpha-hydroxysteroid dehydrogenase [Xenopus (Silurana) tropicalis...
271.0 [0..1] [277..1]

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Predicted Domain #1
Region A:
Residues: [1-287]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIQNEKKHLI LYTGDVTKNL KSGIWNASRI KSNLELVKAL ENVKLTKFTG DGDENLKKNI  60
   61 KVLVPVNEKP QKLDGKQEEY EIIVKLFFLD GENIDIKKRE ETLSQVFYNL HMLFGIDFVS 120
  121 TLVVSFPHIT FLKESGNSSS NEIYDSIDEI PPQEIQSWVD TWKLLEEKVG EGKIGTLGVS 180
  181 EFGVNELQRL ISSVNVVPES TQINIGQNCK LPNDLLNFAD RHHLKLFFHS DPSALLSESE 240
  241 ITSVIHKACP EIPNPARVDW VIRYTILTRH TAVIHQKGYI VQSTYTE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 71.30103
Match: 1ihiA
Description: 3-alpha-hydroxysteroid dehydrogenase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 1.68179794468736 bayes_pls_golite062009
aldo-keto reductase activity 0.756121063182699 bayes_pls_golite062009
binding 0.466080261018594 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 0.0465377885825481 bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors 0.0143508436041874 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle